I break down my semesters like this:
1st sem- It was physically the hardest for me, because I did not know anything about hospitals, and I had all them classes, pharm, patho, assessment, etc
2nd sem- It was the mentally hardest b/c the class adult the teacher was trying to fail everyone that she could fail, it was sooooooo tough, i liked psych but disliked my psych clinical instructor.
3rd sem- this semester didn't have to be hard, but the Peds teacher made it, we continued to take tests on computers, but we could not go back to the questions, therefore, that was new and tough, OB instructor was cool, but people were mean to her, so she was fired for that sem.
4th sem- It was my favorite semester at first, until my clinical instructor kept messing with me, and trying to fail me at clincials, I was doing great in the classroom part.
5th sem- I hated my last sem at first, but after about 2 1/2 months I really liked it, It was my last and ultimately my fav.