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Allergic Reactions

CCU   (1,988 Views 4 Comments)
by BlessedMomRN BlessedMomRN (New Member) New Member

BlessedMomRN has 2 years experience .

1,727 Visitors; 27 Posts

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Hi RNs,

I know the standard of care for an allergic reaction in ER is Solumed, Benedryl, and Randine. I understand the Solumed and Benedryl, but what roles does the Randine play?

Thanks...

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PedsDrNurseTheo has 20 years experience and works as a Peds APRN.

1 Article; 6,081 Visitors; 150 Posts

Ranitidine is a Histamine2 antagonist.

To elaborate somewhat; it is believed that H2 histamine blockers in conjunction with H1 blockers such as diphenhydramine have a synergistic effect; in other words, the two drugs potentiate each other when given together in the presence of a histamine reaction. This is an off-label use of an H2 antagonist, by the way.

Additionally, H2 blockers can relieve the increased acid production which is a potential after effect of the catecholamine dump that will almost assuredly occur in a true histamine reaction.

HTH.

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BlessedMomRN has 2 years experience.

1,727 Visitors; 27 Posts

thanks much!

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