? About abbreviations for bloodwork ordered

[Energizer Bunny]

Dh called the dr. office the other day and they told him they found something in his bloodwork and they want to do more, so they sent us the order and it says this:

DS DNA

ANTI-SMITH ANTIBODIES

What do these mean?

And what does ANA mean in the diagnosis box after something else that I can't read?

Thanks.....

[suzanne4, RN]

Dh called the dr. office the other day and they told him they found something in his bloodwork and they want to do more, so they sent us the order and it says this:

DS DNA

ANTI-SMITH ANTIBODIES

What do these mean?

And what does ANA mean in the diagnosis box after something else that I can't read?

Thanks.....

Evaluation of Anti-ds DNA Antibody Measurement by Using Commercial Kits for Use in a Clinical Laboratory

Kirtikant V. Sheth, MD, FCAP; Morad A. Alkaff, BSc(MT); Sultan A. Bahabri, MD, FRCPC; Kamal M. El Ramahi, MD, FACR; Sultan Al-Sedairy, PhD; Abdullah A. Al-Dalaan, ABIM, FACR

Three hundred and seventy-six consecutive antinuclear antibody-positive sera were tested for anti-ds DNA antibody by using three commercial kits which use 125 I recombinant DNA (radioimmunoassay), highly purified calf thymus DNA (enzyme linked immunosorbent assay) and Crithidia lucilliae (immunofluorescence assay) as substrates. All patients' sera, after reviewing medical records, were classified into three broad groups: Group I (systemic lupus erythematosus), Group II (rheumatic diseases and rheumatoid arthritis), and Group III (nonspecific ANA antibody test positive). A sensitivity, specificity, positive predictive test value and negative predictive test value for Group I against Group II-III (generally these two groups of sera should not show any anti-ds DNA antibody) combined showed for Crithidia lucilliae (IF assay) 58.8%, 93.6%, 82% and 82%, for 125 I recombinant DNA (RIA) assay, 75.8%, 94%, 86.2% and 88.7% and calf thymus highly purified DNA (ELISA) assay using positive cut-off value >100 U/mL, 97.5%, 35%, 42.9% and 24%. The 125 I recombinant DNA (RIA) assay based on the principle of the Farr technique, which is still considered to be the gold standard for anti-ds DNA antibody detection, showed the best specificity and sensitivity among all three methods tested in this study. Ann Saudi Med 1995;15(4):

Both of these exams are essentially used in checking for rheumatoid diseases.

DS DNA stands for double-stranded DNA.

ANA also checks for rheumatoid factors.

Hope that this helps..........................

[kathy_79]

ANA is for antinuclear antibody

dsDNA - double stranded DNA

anti-Sm or anti S mith test is test for lupus, more info you can find on

http://www.uklupus.co.uk/dictac.html

i hope it is helpfull. :)

[Energizer Bunny]

Thank you guys. I appreciate it.