One of the 27 Institutes and Centers at the National Institutes of Health (NIH), the National Institute of Nursing Research supports basic and clinical research by augmenting the scientific knowledge base for the care of individuals across the life span by Registered Nurses (RNs) and other healthcare professionals. RNs comprise the largest group of health care providers, with 2.9 million nationwide. The care they provide must not only be effective, but also improve the health status of patients. To achieve this end, nursing practices must be must constantly updated and validated based on rigorous, peer-reviewed research. Whether this care is delivered in hospitals, long-term care facilities, community or public health centers, or at home, nurses and other members of the interdisciplinary health care team must implement practices that work. NINR's important work fosters advances in nursing practice, improves patient care, informs nurse educators, and attracts new students to the profession.