Clinical research trials RN

I have read many posts about clinical research coordinators but does anyone have experience in the hospital setting as a clinical research trials RN? Do you work with a research team of other RN's? What is your role? Pros and cons? If you take call, what does it entail? I know that some clinical research trials RN's alternate with call, how does each nurse know what to do with the others patients if they are doing different trials? Any information would be much appreciated. Thanks!