Advair risks update?

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Salmeterol and formoterol are long-acting beta-agonists (LABAs) used in the treatment of moderate and severe asthma. LABAs are not an adequate controller therapy by themselves for asthma, & can potentially cause life-threatening asthma attacks if used alone... this risk been known for years, along with problem overuse of albuterol, or any other rescue medication, can place a person at risk for severe asthma attacks, and even death from asthma. A person with asthma therefore should always use an inhaled steroid for treatment of their asthma when a LABA is required.
Due to this issue Advair developed to contain both ingredients: Salmeterol xinafoate = LABA and Fluticasone propionate = steroid.


7/2006:
Alert for Healthcare Professionals - Fluticasone propionate; Salmeterol xinafoate (marketed as Advair Diskus)



Updated: June 30, 2008
Advair Safety and Side Effects - Advair Safety and Black Box Warning


DECEMBER 11, 2008
FDA Panel Says Some Asthma Drugs Too Risky - WSJ.com