Antidepressants and children-New Info - page 2

by lsyorke 1,607 Views | 18 Comments

Here's a link to the recent developments in the recommendations in prescribing ssri's to children. I attended the hearing in Maryland and testified.... Read More


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    I don't know if you caught the newsflash, but several of the worlds most important journals held a conference earlier in the year, and in the last few weeks announced a joint communique. In future they will not publish any evidence from drug trials unless the company concerned has set up a register of all research pertaining to a drug and that all the research is available, not just the positive trials.
    I think its significant that the journals themselves came up with this measure, surely this should have been mandatory years ago and the subject of legislation.... wonder why it has'nt been
    In theory this should mean any medication which does'nt demonstrate a clear benefit, without serious side-effect, never gets out of the lab...... here's hoping... next maybe the provision of drug company perks will be banned by the collective medical profession..... yeah right...
    regards StuPer
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    Stu, this is something we've been fighting for. At least if the clinical trials are tracked from inception in a MANDATORY registry the information will be there for those who want to see. Now getting doctors to read them is another story. Here's the latest report on the Congressional hearing into the FDA

    http://www.nj.com/business/ledger/in...4468320890.xml
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    I work in psych, but I work with adults. When I read about using meds on kids I am bothered. We know that the brain is still developing during adolesent years. We also know that the meds are under constant review even when used in adults. It seems so reckless to use these meds in teens on such a wide basis. so many questions. How do the changing hormone levels in adolesence affect the response to meds? How will the altering of nerotransmitters affect the development of an adolesent brain? ect..I just don't see enough reaserch done with adolesents to justify wide the spread use of neroactive meds in that population.
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    Wam that's exactly what we're saying. Even in trials there is no positive effect, increased negative effect and no long term trials to see how these drugs will effect the adolescent brain. That is very scary!! The fact that these drugs are an off label item means that no continuing studies will be done. So what happens 10 years from now to these kids who have been taking SSRI's?? I shudder to even think about it.
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    I disagree with most of the above posts. All I hear is "what if this" "what if that?", "there are no tests". "it MIGHT be bad" Well what about the kids that are SUFFERING NOW? Lets do studies for 10 years before giving?

    I agree there should be more trials and tests. However, working with kids (adolescents mostly) every day and seeing many of them get POSITIVE effects - ie - less depressed, better affect, decreased S/I. I don't understand how you could want them stopped. Granted it has a NEGATIVE effect on some kids. SO WHAT - what drug does not have side effects? How common is it for SSRI to cause negative effects? What is percentage? As compared to percentage in which it helps?

    I have seen few patients that became worse, or had increased agitation - and the doctor DISCONTINUED the med and went to something else.
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    "Granted it has a NEGATIVE effect on some kids. SO WHAT - what drug does not have side effects?"

    When its your child found hanging at 12 years old at their own hand, then you can tell us SO WHAT!!! That is the most ignorant statement I've ever heard. Do the research before you make offhand comments on something you have no reliable information on. I refer you to the Congressional Hearings going on in Washington regarding SSRI's.I refer you to the FDA Advisory Committee hearing that found No efficacy and increased suicidality in ALL SSRI'S. I refer you to every major newspaper that is carry new information daily. I refer you to the UK who banned these drugs last year for children. Look at those who claim a positive effect and you'll find additional drugs being given ie antipsychotics,tranquilizers.
    It ignorance like this that has allowed this nightmare to continue for years.Yes, children are suffering from depression, I don't deny that. But to continue to use drugs that don't work and are harmful just because we don't have anything else is not a valid argument.Maybe if they ban these drugs the pharmaceutical industry will be forced to do ACCURATE research and development for drugs that DO work.
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    I suffered, and I do mean suffered, from depression and social anxiety disorder from age 15 to age 42. I have been on Zoloft for 7 years and they have been the most wonderful years of my life. If you haven't suffered you don't know what a tremendous gift it is to be able to feel normal. When I was 15 (1970) no one recognized that teens did suffer from depression and no one had a clue that there was such a thing as an anxiety disorder. My school years were miserable. I did not have the benefit of medication or even of any kind of therapy. I survived and do feel that I am stronger because of it however had the drugs & therapy been available to me in those years I would have done anything to get them. I was one miserable teen. Once I graduated things did seem to get better. Nursing school was easier because I was allowed more freedom to come and go from class when I felt a panic attack coming on. I'm making this a long story now and will get on with it. My 15 year old son started having the exact same sx that I had at that age. The feelings he explains to me are the same, the insecurities are the same, he's having panic attacks in school. He has been on Lexapro for about 2 weeks now and is also in therapy. Were just beginning to see some improvement. Someone mentioned that we don't know what these meds are doing to minds that aren't fully developed yet. As for me, if I knew Zoloft would end up shorting my life I would continue to take it. A normal life compared to one full of despair and anxiety is unbelieveable. I was trapped within myself for almost 30 years. Never comfortable. I would not ever consider letting my son go through this hell when meds are available. As a good mother I will continually be on the lookout for any signs of trouble regarding suicide. I think a teen who is depressed would be much more likely to commit suicide if not taking medication. I would have done it myself had I know how to do it. I love life now. I'm very active in my job, in my city, have friends, I feel like I am finally who I am supposed to be. Sign me "Happily Medicated" !!!
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    RN1976Nurse, I wish you and your son the best. At least you go into the medicating of your son with eye's open to the possible side effects. Please watch him closely! My son did wonderful on Paxil for 6 months and then the hell began. Children are not little adults, watch him close!
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    Quote from PRNMEDS
    I disagree with most of the above posts. All I hear is "what if this" "what if that?", "there are no tests". "it MIGHT be bad" Well what about the kids that are SUFFERING NOW? Lets do studies for 10 years before giving?
    Yes, let's do studies for 10 years beforehand. That's usually the standard. Otherwise, you have a bunch of human guinae pigs suffering from unforeseen side effects or, even worse problems years later.

    Perhaps you're not familiar with the famous thalidomide case in the '60s, where this untested drug resulted in the birth of many deformed children. This famous case is one of the many reasons why extensive drug testing is usually required BEFORE it's available to the general public.

    If the drug companies (and the FDA) buried data about suicidal behavior, that's an issue that should have been disclosed publicly, so that both the positive and negative effects could be considered before it was administered to children.

    Quote from lsyorke
    I no longer take any medication without doing my own research and making my own conclusions. Yes, I now read clinical trials!
    This is probably a good idea before taking any drug. I don't rely soley upon physicians either.

    Last edit by Sheri257 on Sep 26, '04


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