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- by bsnanat2 Jun 24, '11i am familiar with fnp's and other primary care np's who have opened nurse managed clinics or other independent practices (even in some states that require a protocol agreement). my question to the group is are there acnp's that have an independent clinic or is acnp independent practice limited to being contracted by a hospital? what are some of the interesting practice scenarios for any np you've seen? (not a school question, but for my own knowledge) thanks!!