Flu Vaccine, enough already! - Page 16

Register Today!
  1. THANK YOU!
    Quote from tshores
    A study published in the October 2008 issue of the Archives of Pediatric & Adolescent Medicine found that vaccinating young children against the flu had no impact on flu-related hospitalizations or doctor visits during two recent flu seasons.
    The researchers concluded that "significant influenza vaccine effectiveness could not be demonstrated for any season, age, or setting" examined.
    • A 2008 study published in the Lancet found that influenza vaccination was NOT associated with a reduced risk of pneumonia in older people.
    This supports an earlier study, published in The New England Journal of Medicine.
    • Research published in the American Journal of Respiratory and Critical Care Medicine also confirms that there has been no decrease in deaths from influenza and pneumonia in the elderly, despite the fact that vaccination coverage among the elderly has increased from 15 percent in 1980 to 65 percent now.
    • In 2007, researchers with the National Institute of Allergy and Infectious
    Diseases, and the National Institutes of Health published this conclusion in the Lancet Infectious Diseases: “We conclude that frailty selection bias and use of non-specific endpoints such as all-cause mortality,have led cohort studies to greatly exaggerate vaccine benefits.”
    • A large-scale, systematic review of 51 studies, published in the Cochrane Database of Systematic Reviews in 2006, found no evidence that the flu vaccine is any more effective than a placebo in children under 2. The studies involved 260,000 children, age 6 to 23 months.
    Bklyn_RN likes this.
  2. Its nice to see that people are still contributing to this post. Thank you Morte.
  3. More anti-vaccination agendas
    It is somewhat disconcerting that there are still allnurses members that are cutting and pasting slanted and sensationalistic attacks on the influenza vaccinations to further the anti-vaccination agenda. Tshores’ post above (#149) is another example. The post purports to be an original authoritative summary of peer-reviewed articles ostensibly demonstrating the overall failure of influenza vaccinations. Below I discuss each of the links in tshore’s post and the actual conclusions in those articles.
    Quote from tshores
    A study published in the October 2008 issue of the Archives of Pediatric & Adolescent Medicine found that vaccinating young children against the flu had no impact on flu-related hospitalizations or doctor visits during two recent flu seasons.
    The researchers concluded that "significant influenza vaccine effectiveness could not be demonstrated for any season, age, or setting" examined.
    The researchers actual formal conclusions from the abstract of the linked article are as follows:

    “In 2 seasons with suboptimal antigenic match between vaccines and circulating strains, we could not demonstrate VE in preventing influenza-related inpatient/ED or outpatient visits in children younger than 5 years. Further study is needed during years with good vaccine match.”

    The failure to find vaccine effectiveness could be result of the poor match between circulating influenza strains and the strains used in that season’s vaccination. More research is recommended.

    Quote from tshores
    A 2008 study published in the Lancet found that influenza vaccination was NOT associated with a reduced risk of pneumonia in older people.
    This supports an earlier study, published in The New England Journal of Medicine.
    The actual quote from the Lancet article abstract is as follows:

    “The effect of influenza vaccination on the risk of pneumonia in elderly people during influenza seasons might be less than previously estimated.”

    The authors of the Lancet article do not conclude that influenza vaccination was useless for elderly people, only that it's efficacy may not be as high as reported.

    The second link provided by tshores in this quote does not lead to a peer reviewed article in the New England Journal of Medicine --- but rather to one of Mercola.com’s web pages.
    Quote from tshores
    Research published in the American Journal of Respiratory and Critical Care Medicine also confirms that there has been no decrease in deaths from influenza and pneumonia in the elderly, despite the fact that vaccination coverage among the elderly has increased from 15 percent in 1980 to 65 percent now.
    The referenced article does not discuss vaccine uptake rates, but is a study of mortality rates. The actual conclusions of the researchers in this article is as follows:
    “The 51% reduction in mortality with vaccination initially observed in patients with pneumonia who did not have influenza was most likely a result of confounding. Previous observational studies may have overestimated mortality benefits of influenza vaccination.”

    The article does not confirm that increased vaccine uptake has failed to decrease elderly deaths from influenza and pneumonia, only that there seems to be fewer mortality benefits from vaccinations among the elderly.

    Quote from tshores
    In 2007, researchers with the National Institute of Allergy and Infectious Diseases, and the National Institutes of Health published this conclusion in the Lancet Infectious Diseases: “We conclude that frailty selection bias and use of non-specific endpoints such as all-cause mortality,have led cohort studies to greatly exaggerate vaccine benefits.”
    While this is a direct quote, the conclusions are not fully accepted in the scientific community. Conveniently, the original author of this material fails to cite the rejoinder comments about this article by several authors in The Lancet Infectious Diseases : Volume 8, Number 8, 1 August 2008
    Quote from tshores
    A large-scale, systematic review of 51 studies, published in the Cochrane Database of Systematic Reviews in 2006, found no evidence that the flu vaccine is any more effective than a placebo in children under 2. The studies involved 260,000 children, age 6 to 23 months.
    The strident interpretation of the effectiveness of vaccines compared to a placebo for children under 2 years is not supported by a reading of the authors’ actual conclusions which are as follows:

    “Influenza vaccines are efficacious in children older than two years but little evidence is available for children under two. . . If immunisation in children is to be recommended as public-health policy, large-scale studies assessing important outcomes and directly comparing vaccine types are urgently required.”

    People need to do their own research and come to their own reasoned opinions.

    The post by tshores demonstrates the perils of cutting and pasting information from the internet and passing it off as original effort in an attempt to further an anti-vaccination agenda.
    llg, chenrezigheart, HouTx, and 1 other like this.
  4. LOL, I just worked a double, and the brain is in idle mode. But some one did try to do research and get it published but catch 22, because the vacine JUST HAS TO WORK they couldn't get their refutation published. You know, "pot has no medicinal value, there for you can't do any research that it does."
    Quote from Laidback Al
    More anti-vaccination agendas
    It is somewhat disconcerting that there are still allnurses members that are cutting and pasting slanted and sensationalistic attacks on the influenza vaccinations to further the anti-vaccination agenda. Tshores’ post above (#149) is another example. The post purports to be an original authoritative summary of peer-reviewed articles ostensibly demonstrating the overall failure of influenza vaccinations. Below I discuss each of the links in tshore’s post and the actual conclusions in those articles.


    The researchers actual formal conclusions from the abstract of the linked article are as follows:

    “In 2 seasons with suboptimal antigenic match between vaccines and circulating strains, we could not demonstrate VE in preventing influenza-related inpatient/ED or outpatient visits in children younger than 5 years. Further study is needed during years with good vaccine match.”

    The failure to find vaccine effectiveness could be result of the poor match between circulating influenza strains and the strains used in that season’s vaccination. More research is recommended.



    The actual quote from the Lancet article abstract is as follows:

    “The effect of influenza vaccination on the risk of pneumonia in elderly people during influenza seasons might be less than previously estimated.”

    The authors of the Lancet article do not conclude that influenza vaccination was useless for elderly people, only that it's efficacy may not be as high as reported.

    The second link provided by tshores in this quote does not lead to a peer reviewed article in the New England Journal of Medicine --- but rather to one of Mercola.com’s web pages.

    The referenced article does not discuss vaccine uptake rates, but is a study of mortality rates. The actual conclusions of the researchers in this article is as follows:
    “The 51% reduction in mortality with vaccination initially observed in patients with pneumonia who did not have influenza was most likely a result of confounding. Previous observational studies may have overestimated mortality benefits of influenza vaccination.”

    The article does not confirm that increased vaccine uptake has failed to decrease elderly deaths from influenza and pneumonia, only that there seems to be fewer mortality benefits from vaccinations among the elderly.


    While this is a direct quote, the conclusions are not fully accepted in the scientific community. Conveniently, the original author of this material fails to cite the rejoinder comments about this article by several authors in The Lancet Infectious Diseases : Volume 8, Number 8, 1 August 2008

    The strident interpretation of the effectiveness of vaccines compared to a placebo for children under 2 years is not supported by a reading of the authors’ actual conclusions which are as follows:

    “Influenza vaccines are efficacious in children older than two years but little evidence is available for children under two. . . If immunisation in children is to be recommended as public-health policy, large-scale studies assessing important outcomes and directly comparing vaccine types are urgently required.”

    People need to do their own research and come to their own reasoned opinions.

    The post by tshores demonstrates the perils of cutting and pasting information from the internet and passing it off as original effort in an attempt to further an anti-vaccination agenda.
  5. To Laidback Al:
    Then why are you including only the sugarcoated Conclusions/Interpretations instead of the Results and Findings in those studies?

    Archives of Pediatric and Adolescent Medicine

    Results:
    During the 2003-2004 and 2004-2005 seasons, 165 and 80 inpatient/ED and 74 and 95 outpatient influenza cases were enrolled, while more than 4500 inpatient/ED and more than 600 outpatient subcohorts were evaluated, respectively. In bivariate analyses, cases had lower vaccination rates than subcohorts. However, significant influenza VE could not be demonstrated for any season, age, or setting after adjusting for county, sex, insurance, chronic conditions recommended for influenza vaccination, and timing of influenza vaccination (VE estimates ranged from 7%-52% across settings and seasons for fully vaccinated 6- to 59-month-olds).

    I agree that much more study is needed--but by independent researchers with no financial ties to the pharmaceutical companies. They just proved that you were not "protecting" your patients for at least 2 years in a row.

    2008 Lancet article:

    FINDINGS:
    1173 cases and 2346 controls were included in the study. After we adjusted for the presence and severity of comorbidities, as defined by chart review, influenza vaccination was not associated with a reduced risk of community-acquired pneumonia (odds ratio 0.92, 95% CI 0.77-1.10) during the influenza season.
    INTERPRETATION:

    The effect of influenza vaccination on the risk of pneumonia in elderly people during influenza seasons might be less than previously estimated.

    Interpretation that you quoted is kind of watered down, wouldn't you say? I do realize they have to state 'may' and 'might' because they are interpreting only one study, but I think the whole study should be read.

    In the Lancet Infectious Diseases--of course, scientists are not all in agreement on vaccinations or on a lot of things, for that matter. Doesn't mean we shouldn't hear them.

    And in the Cochrane Database under the Main Results:
    "In children under two, the efficacy of inactivated vaccine was similar to placebo."

    I am not anti-vaccination. I've been vaccinated for several things. I am against flu vaccinations being a condition of employment when I personally do not feel it is protecting anyone much of the time and is not harmless. I agree with you that people should do their own research, but they don't have to agree with me to have a "reasoned opinion."

    Bklyn_RN and morte like this.
  6. Guide
    enlightening to say the least~
  7. Quote from mindlor
    First of all an American includes the Canda, Mexico, and all of the central and south AMERICAN nations So I think you mean as a citizen of the USA. Second of all...God given? I think not....you get your rights from the Constitution and the Bill of Rights.

    That said you are correct. As a citizen you have the right to refuse. as a healthcare worker you have the right to get the shot or wear a mask all shift every shift. Also, you have the right to change careers.
    Wow! Can't remember the last time I heard a Canadian or Mexican or Central American refer to themselves as an 'American'. Pretty darn sure, the world over, when someone says, "Oh you're an American." They are thinking about those of us from AMERiCA...the United States of AMERICA....nowhere else.


    If you refer to yourself as an AMERICAN and you are not a citizen of the United States of America, get over it and try a little pride in the country you do come from!!!
  8. Provincial, much? When I was in Korea, someone asked if I was from the USA and I said yes, I am from America, and they said no, the USA. I had to admit they were correct. This whole hemisphere is 'AMERICA.'
    Quote from whatdoIdonow?
    Wow! Can't remember the last time I heard a Canadian or Mexican or Central American refer to themselves as an 'American'. Pretty darn sure, the world over, when someone says, "Oh you're an American." They are thinking about those of us from AMERiCA...the United States of AMERICA....nowhere else.


    If you refer to yourself as an AMERICAN and you are not a citizen of the United States of America, get over it and try a little pride in the country you do come from!!!
  9. Guide
    Quote from morte
    provincial, much? when i was in korea, someone asked if i was from the usa and i said yes, i am from america, and they said no, the usa. i had to admit they were correct. this whole hemisphere is 'america.'
    things that make you go hmmm ....
  10. Quote from morte
    Provincial, much? When I was in Korea, someone asked if I was from the USA and I said yes, I am from America, and they said no, the USA. I had to admit they were correct. This whole hemisphere is 'AMERICA.'
    We'll they would be wrong...WE are AMERICANs...From the United States of AMERICA...
    A M E R I C A I repeat for the deliberately obtuse! Culturally, historically and in name, we are the only AMERICANs.

    Just like there are...Canadians, Mexicans, Costa Ricans, Panamanians, Hondurans, Guatemalans, Venezuelans, Columbians, Peruvians, Bolivians, Argentinians, Chileans, Brazilians...funny how people show their pride as the peoples of the country they live in by naming themselves after their country name.

    One wonders, if you are American, why you don't show some pride in it and why you allow yourself to be tuitored by foreigners with who knows what as a politically correct agenda.....geez!