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Drug Cocktail Effective Against Tamiflu Resistant Swine Flu



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Oct 28, 2009 07:21 PM

Drug Cocktail Effective Against Tamiflu Resistant Swine Flu

by indigo girl allnurses Guide

http://www.medicalnewstoday.com/articles/168932.php

The Birmingham area seems to be the place for new antiviral treatment options for swine flu virus. Peramivir came from this region also.

It is expected that at some point swine H1N1 will become Tamiflu resistant as has seasonal H1N1. Cases have already occurred, even when the patient never had received Tamiflu indicating that this is a naturally occurring event. Mostly I have stopped trying to document this as there are too many other things to keep track of with this pandemic.

The effectiveness of this treatment option may prove to be very important in the future for more than just swine flu. It's well worth a read of the entire article. I expect that we will hear more about this in the future.

Originally Posted by www.medicalnewstoday.com
"These findings suggest strongly that the triple combo is highly synergistic against virus replication, meaning it strikes multiple targets within H1N1 flu and other strains," Prichard says. "Only human testing will determine for sure, but this combo has the potential to be the antiviral therapy of choice for serious flu infection and to address Tamiflu resistance."

The synergy was seen in swine flu and seasonal flu strains, as well as H3N2 seasonal flu and the highly pathogenic H5N1 avian influenza strain, Prichard says. The dosing and timing of the combo mixture is protected information by Adamas. The company is starting human testing in the Southern Hemisphere, and has plans to begin human testing in North America once approval is obtained.

Because flu infection typically lasts for shorter periods of time than many other chronic infections, the three-pronged antiviral approach means the circulating strains of flu virus may not have time to develop resistance to the combo, Prichard says. "That's why this research is so timely, and why antiviral safety and testing data is crucial.
(hat tip crofsblog)


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