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Oxaliplatin question



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May 06, 2009 02:07 AM

Oxaliplatin question


I have read the warnings to mix Oxaliplatin in D5W only. Does anyone know why you can't mix Oxaliplatin in Normal Saline? And if you do make that mistake what the effects would be to the patient?

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chloride, effects, normal saline, oxaliplatin
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3 Comments
No. 1
from ghillbert
Old May 06, 2009, 02:23 AM

Default Re: Oxaliplatin question
Apparently NS or any chloride ions inactivate the drug. Serious potential adverse effect on the patient, obviously. This would need to be reported to the medical team.

http://products.sanofi-aventis.us/el.../eloxatin.html

http://stp.cancercare.ns.ca/document...iplatin_dm.pdf
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No. 2
from nurseDee03
Old May 06, 2009, 02:42 AM

Default Re: Oxaliplatin question
Thank you. This did not occur, it was a question asked by a patient and I could not find the answer on the net. Thanks for responding so quickly.
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No. 3
from ghillbert
Old May 06, 2009, 02:50 AM

Default Re: Oxaliplatin question
If you ever need drug info online, try searching "drugname" + "product information" and you'll usually get a link to the manufacturer information.
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