thats weird It must just be the area i am from where the route matter
but seriously when given po it causes cotraction and does not seem to ripen cervix as well. when given po our patients will usually get 4 doses and then get pitted. where as ones given vagianally usually deliver after 2 or 3rd dose never make it to pit.
have only had 2 failed inductions with cytotec placed vaginally over last yr. and had approx 8 failed via PO route. seems to be the same at the other 2 hospitals in our area.
the doctors here were ordering it po because the nurses were refusing to place it vaginally. i was the only one at the 3 hospitals that would place it.now it is done on a routine basis.
and as far as the off label use i was told that the manufacturer had recently changed the off label use. not sure if it is true been meaning to check it out. does anyone know what the most recent literature on it says?
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