Ibuprofen in pregnancy

I completed a maternity placement earlier this year, and we had a pt come in who had passed out in the shower.
She had c/o headaches, and advised that she had taken ibuprofen (actually I think it was neurofen plus - 200mg ibuprofen and 12.8mg codiene, we can get it OTC here) and her mother who was a midwife had told her it was ok to take.

I have read that it isn't good to take ibuprofen esp in the last trimester. This lady was approx 36 weeks.
The m/w who was with me, told her that they don't recommend it, and she should probably stick to paracetomal.

I was looking into the studies on iboprofen and it says that taking it in the last trimester can lead to the septal duct (?) closing prematurely in the heart which can lead to persistant pulmonary hypertension in the newborn.

I was just wondering, as the study didn't go into rates etc, but has anyone here actually seen this as a result of ibuprofen use?

And does anyone know the pathophys behind why iboprofen would cause this?

It just seems to me that if leads to this then why isn't there more of a fuss made about using ibuprofen in preg??

And how much is too much? Because this woman use it I think it was two doses (400mg each dose) when do we look at monitoring for the heart problems?