Need help learning Alpha/Beta/Channel Blockers

  1. Hello,
    Can anyone break down Alpha, Beta, and Calcium Channel blockers?
    Alpha-1, Alpha-2, Beta-1, Beta-2 etc...
    Usually I can grasp a concept pretty easily, but this has me pulling out my hair! Any input, explanation, websites would be greatly appreciated.

    An instructor was trying to find "the pig picture" I guess this picture breaks it down really well. She says once you see the pig pic you will never forget how it all works. I have yet to find this piggy!

    Anyone know of "The Pig"??

    Thanks!
    •  
  2. 9 Comments

  3. by   XIGRIS
    Quote from cjandmama
    Hello,
    Can anyone break down Alpha, Beta, and Calcium Channel blockers?
    Alpha-1, Alpha-2, Beta-1, Beta-2 etc...
    Usually I can grasp a concept pretty easily, but this has me pulling out my hair! Any input, explanation, websites would be greatly appreciated.

    An instructor was trying to find "the pig picture" I guess this picture breaks it down really well. She says once you see the pig pic you will never forget how it all works. I have yet to find this piggy!

    Anyone know of "The Pig"??

    Thanks!

    Pig? or Big picture? If you see the Pig oh please tell me... Im curious...
  4. by   CardioTrans
    There is a wonderful information page on all cardiac drugs at www.heartcenteronline.com

    You can access as a provider or a patient. Very good info to help you understand. Good luck!
  5. by   crb613
    Beta blockers:
    B1 selective vs. B1-B2 non-selective
    A through N: B1 selective: Acebutalol, Atenolol, Esmolol, Metoprolol.
    O through Z: B1, B2 non-selective: Pindolol, Propanalol, Timolol.

    Adrenoceptors: vasomotor function of alpha vs. beta
    ABCD:
    Alpha = Constrict.
    Beta = Dilate.

    Beta-1 vs Beta-2 receptor location "You have 1 heart and 2 lungs":
    Beta-1 are therefore primarily on heart. Beta-2 primarily on lungs.
    Hope this helps
  6. by   mwbeah
    There is a book named "pharmacology made ridiculously simple" which costs about 8 bucks on www.half.com , it breaks things down very simply and has nice cartoonish diagrams which details your questions fairly well.

    Mike
  7. by   cjandmama
    You all are wonderful! Thank you so much. I love the mneumonics! I may have to check out that book as well. Thank you. Thank you. Thank you!
    75 days until Graduation!!!!
  8. by   tinkerwomp
    In school, I knew the action, but confused the names. B-blockers have the -lo in the name (as in "blockers") - propanolol, etc. ACE are -pril. Ca channels are pines or mil at the end. Stupid way, but it helped jog my memory.
  9. by   Reddy,RN
  10. by   mendu
    hello cjandmam,
    what my instructor gave us is:
    1. ca channel blockers:

    A ction - block ca access to cells
    H ypotension, headache
    E dema
    C onstipation
    K now to watch for worsening of CHF and heart block

    2. blockers s/e
    B radycardia
    L ibido decrease
    brOnchospasm
    C HF, conduction abnormalities
    K nown hypotension
    E xhaustion, emotional depression
    R educed recognision of hypoglycemia

    3. alpha 1 and 2 blockers: doxazosin, prazosin, terazosin;
    A ction - block alpha adrenergic receptors in ANS causing vasodilation, lower
    BP
    S yncope,sexual dysfunction common
    I ncreased drowsiness, HR, orthostatic hypotension
    N eed to recline 3-4 hours after 1st dose

    others:
    4. diuretic
    D iet - low sodium, increse potassium intake, unless taking potassium sparing
    I ntake & output, daily weight
    U ndesirable effects - fluid and electrolytes imbalance, dizziness, hypotension
    R eassess BP, HR, electrolytes
    E lderly care - monitor for decreased kidney function (excretion of drugs)
    T ake AM, if bid before 6pm, prevent nocturia
    I ncreased orthostatic hypotension
    C ancel alcohol use

    5. ACE inhibitors (enarapril, lisinopril)
    A ct - prevent conversion of angiotensin I to II
    P ruritus
    R ash
    I ncreased hypotension. tachycardia, angioedema, cough, infection
    L ousy taste, headache

    6. ARB (losartan, valsartan)
    A ct - prevent angiotensin II to bind to its receptors
    A dminister with or without food (watch GI upset)
    R enal function monitor!!! (elderly!!!)
    B lock vasoconstriction (lower BP)
    S ubstitutes of sodium and potassium DO NOT USE

    7.Loop diuretics
    A ct - rapid diuresis, block chloride pump in ascending loop of henle, causing decrease reabsorption of sodium and chloride,
    L oss effectivness if given with NSAIDs
    I ncreae action of anticoagulant

    H ypokalemia - monitor closely
    O totoxicity
    H yperglycemia - moniotr blood glucose

    hope this help and good luck to all of you with nursing,
  11. by   cjandmama
    You all have helped me a lot. I greatly appreciate your knowledge and time taken to help me out! Tomorrow is my 2nd day of leadership. Graduation is so close I can almost see the light....

    Thanks again!!

close