Hey guys! I have a math exam on pediatric doses this Friday. I was doing the study guide and came across 4 problems I have no idea how to solve. I tried looking up methods or formulas, but for some reason I'm not getting it. I posted the questions I'm having trouble with below along with the correct answers (given by my teacher). If you guys can help me go over it or guide me to solve it...you'd be a life saver!!
Thank-you so much
[COLOR=#000000]1) Order is for Methyl-medrol 12 mg/kg over 15 minutes. Pt. weighs 27 kg. 500 mg vial is provided, to be reconstituted with 9.5 ml of 0.9% sodium chloride to yield a 50 mg/ml concentration. The solution must be diluted further to 45 mg/ml, and the tubing flushed with 12 ml. What will the pump rate be? ANSWER= 76.8 ml/hr
2) Your pediatric patient is to receive Hexamycin 225 mg IV intermittent q 6 hours. This is a safe dose. Your facility’s tubing needs to be flushed with 20 ml. The administration directions from the facility’s drug guide are as follows: Administer Hexamycin by intermittent IV infusion over 60 minutes at a concentration not to exceed 5mg/ml.
a. What will the dilution of medication be? ANSWER= 45 ml/hr
b. What rate will you infuse the solution at to infuse the total volume of the med. and flush? ANSWER= 65 ml/hr
3) Pt. weighs 52 kg. Give Ventax, 200 mg over 15 minutes q12 hours. The minimal volume that the drug may be diluted in 15 mg/ml. The tubing should be flushed with 15ml. The recommended range for Ventax is 2.5 – 3.5 mg/kg/dose q12h; severe infection is 3.6 – 4 mg/kg/dose. Max is 1g/day. Is the dose as ordered safe? If so, What will the pump rate be?
ANSWER= Safe= 130-208 mg/dose; pump rate= 113.2 ml/hr
4) Your pediatric patient is ordered Piplin/bactotaz 600mg IV intermittent q6h. Drug book guideline states: Administration: Piplin/bactotaz may be administer by I.V. intermittent over 30 minutes at a maximum concentration of 200mg/mL (Piplin component); however, concentrations equal to or < 20 mg/ml are preferred; if the patient is on concurrent aminoglycoside therapy, separate piplin/bactotaz administration from the aminoglycoside by at least 45 - 60 minutes. The tubing flush is 20 ml.
a) What volume will you dilute this medication in? ANSWER= 30 ml
b) What rate in ml/hr will you infuse your IV to infuse the medication and flush? ANSWER= 100 ml
again, thanks for much for any type of help! I really appreciate it.
Question 1: 76.8 ml/hr is not correct. You are to infuse 12 mg/kg of Methylmedrol. If your patient weighs 27 kg, how many mg of Methylmedrol should you administer? If you are to dilute to 45 mg/mL, how many mL will this be? When calculating infusion rate for an antibiotic a day flush, the infusion rate is based upon the volume of the antibiotic alone, not the combined volume of the antibiotic and flush. The flush vole is then infused at the same rate as the antibiotic.
Question 2a: 45 mL is correct. How do you think that they arrived at this volume?
Question 2b: 65 mL/hour is not correct; this would deliver the dose of Hexamycin in ~41.5 minutes. The total volume of Hexamycin is 45 mL. If you want to administer this over 1 hour, how fast should it be administered? The Hexamycin dose is to be infused at this rate. The 20 mL flush is the infused at the same rate as the Hexamycin.
Question 3: There are two dosing ranges of Ventax; the “recommended” dose and the dose for “severe infection.” The “recommended” dose is 2.5 – 3.5 mg/kg, and the dose fore “severe infection” is 3.6 -4 mg/kg. Whether 200 mg is a safe dose depends on how/what the patient is being treated for. 113.2 mL/hour is not correct. 200 mg of Vestax, at 15 mg/mL equals how many mL? And will be infused at what rate? Yhe 15 mL of flush is infused at the same rate as the Ventax dose.
Question 4a: 30 mL is correct. Again, how do you think that they arrived at this volume?
Question 4b: 100 mL/HR is not correct. Again, as with the Hexamycin and Ventax you calculate the infusion rate for the antibiotic alone; not the volume for the antibiotic and flush combined. After the antibiotic infusion is completed, the flush volume is infused at the same rate as the antibiotic.
Last edit by chare on Jan 10