Protect Your Patients When Giving Promethazine (Phenergan) - page 2

by TheCommuter Asst. Admin

22,453 Views | 22 Comments

Promethazine is a widely-used medication in healthcare facilities because it has multiple uses. It contains antiemetic (anti-nausea), sedative, antihistamine, and anti-motion sickness properties and can be administered orally,... Read More


  1. 3
    Thanks for sharing this important warning! We need to be careful especially when administering vesicants such as dopamine, epinephrine and amiodorone. That's just a few that come to mind, though there are many more. I wish hospitals would insist on using central lines for these medications as is preferred, but to save money, many times only a peripheral lines is used. We need to be careful as we don't want anyone to lose a hand or arm which can happen if these vesicants infiltrate the skin thru a non patent IV.
  2. 3
    Thanks for a review of the current recommendations and policies. I was quizzed on the difference between using Zofran and Phenergan and besides the drowsiness, this is the most important difference.
  3. 1
    Thanks for good information. You have helped me and my patients a lot!
    TJ'sMOM likes this.
  4. 1
    Zofran is the drug of choice at my hospital but when that doesn't work, they get switched to Phenergan. IV injection is absolutely not allowed per hospital policy. Some docs have made a fuss but now they know. We only give it PO or by deep IM, and the IM injection still hurts.
    cherryames1949 likes this.
  5. 1
    Quote from brandy1017
    I wish hospitals would insist on using central lines for these medications as is preferred, but to save money, many times only a peripheral lines is used. We need to be careful as we don't want anyone to lose a hand or arm which can happen if these vesicants infiltrate the skin thru a non patent IV.
    I wish that, too. The only time someone gets a central line put in at my hospital is if they have horrible veins or if we know they're going to be in for awhile. Some patients who didn't expect to be in the hospital for awhile end up being there for awhile, and then by the time they think of putting in a central line, the patient is then ready to be discharged. It's scary administering vesicants through a simple peripheral IV!
    cherryames1949 likes this.
  6. 1
    once again another great article form the commuter.... mahalo & aloha~
    TJ'sMOM likes this.
  7. 2
    Thank you for this article. I've given Phenergan once as a student, diluted in 10 mL NS of course! I've not given it in IM form, yet. How much NS would be needed to dilute IM Phenergan? And is it best to use the gluteal muscles over the vastus lateralis when giving IM Phenergan?

    These are the topics needed more than "My Preceptor is a Bully", or "Old nurse vs. new nurse".
    E.niles and zero. like this.
  8. 0
    I learned my lesson with phenergan the HARD WAY.

    During those days of giving it via slow IV push, I had one patient who immediately went into seizure, turned out to be a TIA and it really got me anxious and couldn't get over it for a week.

    I would never forget how I felt that day.
  9. 0
    Quote from whichone'spink
    I've not given it in IM form, yet. How much NS would be needed to dilute IM Phenergan?
    Nobody dilutes IM Phenergan in clinical practice. You give it deep IM, and you must use a needle that's at least 1.5 inches long. Never give it subcutaneously because it will cause damage. When injecting, always give it deep IM.
    Quote from whichone'spink
    And is it best to use the gluteal muscles over the vastus lateralis when giving IM Phenergan?
    You'll be fine as long as you remember to give it deep IM. Personally, I do not like using the gluteal muscles because I am always afraid I'm going to hit the sciatic nerve with the long needle.
    Quote from whichone'spink
    These are the topics needed more than "My Preceptor is a Bully", or "Old nurse vs. new nurse".
    I certainly agree with you on that point.
  10. 0
    i learned my lesson many moons ago, and since then i always suggest to give it deeply im.


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