How to reconstitute amoxicillin?

  1. 0 I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.

    Thank you
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  3. Visit  Tazike profile page

    About Tazike

    Joined Feb '11; Posts: 1.

    12 Comments so far...

  4. Visit  noahsmama profile page
    3
    Is there a pharmacy where you work that you can call and ask? If not, can you ask any of the other nurses where you work? I think they would be a better source of information than an Internet board.
    mountainview210, Altra, and BabyLady like this.
  5. Visit  billyboblewis profile page
    0
    Check the pdr or other Drug manual.
  6. Visit  GHGoonette profile page
    2
    Here's a link that gives the info:

    http://www.google.co.za/url?sa=t&sou...upSvU5vUHdlztg
    Last edit by GHGoonette on Feb 25, '11
    Chin up and netglow like this.
  7. Visit  GM2RN profile page
    3
    Are you sure you checked the bottle well? Ours comes with directions right on it, but the print is quite small and easy to miss.
  8. Visit  loriangel14 profile page
    2
    Does your floor not have a IV med handbook. Our floor has one that gives all info on preparing and administering. Our amoxicillin comes with directions on the bottle too.
    mountainview210 and sevensonnets like this.
  9. Visit  GHGoonette profile page
    1
    Bottle Size Amount of Water Required for Reconstitution
    100 mL 74 mL
    150 mL 111 mL

    Each teaspoonful (5 mL) will contain 250 mg amoxicillin.

    I checked that link-I see it only mentions 200 and 400mg doses. The above is the correct reconstitution, but the OP mentions a 120ml bottle. Op, I would recommend that you first check what the quantity is supposed to be after reconstitution; if you are correct and it is supposed to be 120ml, the amount of water, judging by the above table, would be in the region of 89ml.
    MassED likes this.
  10. Visit  studentpn73 profile page
    0
    Hi, hope you dont mind, working on this for practice and got 90 mL !!

    I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?
    Thanks
  11. Visit  GHGoonette profile page
    0
    Quote from studentpn73
    Hi, hope you dont mind, working on this for practice and got 90 mL !!

    I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?
    Thanks
    You need a pharmacist to answer that one for you. As far as I remember, amoxil always came in a standard strength, ie multiples of 125mg. I confess, I never came across the other doses mentioned. I could be wrong, but I think the final strength was not dependent on differing strengths of the active substance itself, but in the quantity of powder for reconstitution in the bottle, and the amount of water that was consequently added to it. This was according to instructions on the bottle or the package insert.

    It's been about 25 years since I had to fiddle with reconstituting suspensions, so my memory is not to be relied on
  12. Visit  studentpn73 profile page
    0
    Ahh just saw it there and thought Id work on it for fun...just passed the math exam but hey
  13. Visit  Kabamba profile page
    0
    The Bottle of the generic drug Novamoxicillin contains 5000 mg amoxicillin as trihydrate. You are asked to add 60 ml water in two portions and shake well to make 100 ml of suspension. Each 1 ml conatains 50 mg of amoxicillin.
    1ml = x x= 100 ml of suspension
    50 5000 mg

    Quote from Tazike
    I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.

    Thank you
  14. Visit  Kabamba profile page
    0
    That was the first clue I gave you. Therefore, concerning the 120 ml of suspension, you need:
    (250 mg : 5 ml) = (x mg:120ml)
    x= 6000 mg.
    Therefore, you need a powder of amoxicillin as trihydrate to make a suspension of 120 ml.
    I think this will be helpful.
  15. Visit  All4NursingRN profile page
    0
    In my use of amox for peds I know the bottles we get says to reconstitute with 90 ml's total, but to add 1/3 at a time. So I add about 30 ml's at a time, mix then add, it still ends up half mixed, the other half hard, so I usually manually mix it, don't know if I'm using the best technique, but I get it all mixed.


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