How to reconstitute amoxicillin?

I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.
Thank you 

Feb 25, '11Is there a pharmacy where you work that you can call and ask? If not, can you ask any of the other nurses where you work? I think they would be a better source of information than an Internet board.



Feb 25, '11Are you sure you checked the bottle well? Ours comes with directions right on it, but the print is quite small and easy to miss.

Feb 25, '11Does your floor not have a IV med handbook. Our floor has one that gives all info on preparing and administering. Our amoxicillin comes with directions on the bottle too.

Feb 25, '11Bottle Size Amount of Water Required for Reconstitution
100 mL 74 mL
150 mL 111 mL
Each teaspoonful (5 mL) will contain 250 mg amoxicillin.
I checked that linkI see it only mentions 200 and 400mg doses. The above is the correct reconstitution, but the OP mentions a 120ml bottle. Op, I would recommend that you first check what the quantity is supposed to be after reconstitution; if you are correct and it is supposed to be 120ml, the amount of water, judging by the above table, would be in the region of 89ml. 
Feb 26, '11Hi, hope you dont mind, working on this for practice and got 90 mL !!
I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?
Thanks 
Feb 26, '11Quote from studentpn73You need a pharmacist to answer that one for you. As far as I remember, amoxil always came in a standard strength, ie multiples of 125mg. I confess, I never came across the other doses mentioned. I could be wrong, but I think the final strength was not dependent on differing strengths of the active substance itself, but in the quantity of powder for reconstitution in the bottle, and the amount of water that was consequently added to it. This was according to instructions on the bottle or the package insert.Hi, hope you dont mind, working on this for practice and got 90 mL !!
I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?
Thanks
It's been about 25 years since I had to fiddle with reconstituting suspensions, so my memory is not to be relied on 
Feb 26, '11Ahh just saw it there and thought Id work on it for fun...just passed the math exam but hey

Feb 2, '12The Bottle of the generic drug Novamoxicillin contains 5000 mg amoxicillin as trihydrate. You are asked to add 60 ml water in two portions and shake well to make 100 ml of suspension. Each 1 ml conatains 50 mg of amoxicillin.
1ml = x x= 100 ml of suspension
50 5000 mg
Quote from TazikeI'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.
Thank you 
Feb 2, '12That was the first clue I gave you. Therefore, concerning the 120 ml of suspension, you need:
(250 mg : 5 ml) = (x mg:120ml)
x= 6000 mg.
Therefore, you need a powder of amoxicillin as trihydrate to make a suspension of 120 ml.
I think this will be helpful. 
Feb 4, '12In my use of amox for peds I know the bottles we get says to reconstitute with 90 ml's total, but to add 1/3 at a time. So I add about 30 ml's at a time, mix then add, it still ends up half mixed, the other half hard, so I usually manually mix it, don't know if I'm using the best technique, but I get it all mixed.