Amiodarone drip

Curious to know if anyone else has noticed a delayed reaction to amiodarone drip.

My patient was on amiodarone via a left mid lower forearm site. Natrecor was infusing via the left hand. Upon assessment at 0730 there was a gof ball sized edematous area just above a 3rd saline lock.
By 10 am the left hand site developed some redness and was dc'd. The amiodarone site was tender and dc'd. thirty minutes later a Picc lin was initiated in special procedures.
At 1315 he returned to the floor-Picc in the upper right arm.
By 1330 the family called me to the room. His left arm was suddenly edematous from fingers to just below the axilla. Vein enlargement, redness and warmth were noted beginning just above the AC. He complained of numbness and tingling to the total arm.
Today, it has decreased to 2+ edema, continues to have sli redness and altho the vein is not distended is still visible and tender to touch. Kpad continues as ordered.
The IV therapist told me tonite that a patient in the CCu had a similar incident 4 days ago.
Neither the pharmacist or his team could find any information or similar occurrences listed.

Can anyone else relate? Does anyone have any info?
Was this a phlebitis caused by a drip dc'd 4 hrs prior?

Thanks.