Manager is blocking advancement - should I go?

Hi - here's the problem: I recently posted for a clinical leader position for which I was qualified. I was encouraged by colleagues and supervisors to apply. My floor manager did not agree and after much (painful) discussions it was revealed that she has a "personality clash" with me. The reasons she gave were trivial and not based on my experience or past performance. I am concerned now about repercussions but have worked on this floor in a charge role for 7 years. I have always received excellent performance reviews in the past but am nervous about what is to come. Do I cut my losses and transfer to another unit? Has anyone had a similar issue and how did you address it? Thanks for any help you can provide.