Working nights and weekends is hard in any profession, so this may be coloring your impression of nursing?
Also, remember that the first year out of school is always the hardest because of the learning curve.
When I graduated with med tech, I worked 3rd shift for 2 years and hated it. Now I'm on second shift at a great hospital and loving it. Once you get a year or two of experience under your belt, you will have your pick of jobs. Try talking to all the nurses you know to find out what they like about their area (peds, ICU, home health, parish nursing, etc.).
My advice is to stick it out for a while longer, and then go searching for your dream job

Good luck!
Nursing News