Could anyone please please :-) give me to formula for calculating the dosage and ranges for dopamine and dobutamine? I can't seem to find it. And some people explain it making it difficult.
Yep, AlaskaKat, you got it right for the # mg. Everyone kind of calculates things in a different order, depending on where you've worked before, etc. but it all comes out the same in the end! Here is how we do it:
For standard concentration (10mcg/kg/min=1cc/hr) add 60mg times the # kg of the baby. Standard for 3 kg baby:
3 x 60= 180mg Dop should be added to 100cc
180mg x 1000= 180,000mcg Dop in 100cc IV bag
180,000mcg divided by 100= 1,800 mcg/cc Dop
1,800mcg/cc divided by 3kg= 600 mcg/kg/cc
600mcg/kg/cc divided by 60 minutes= 10mcg/kg/min per 1cc
For double concentration (20mcg/kg/min=1cc/hr) multiply the baby's weight by 120mg. Double for 500 gram baby:
0.5 x 120 = 60mg Dop added to 100cc
60mg x 1000= 60,000 mcg Dop in 100cc IV bag
60,000mcg divided by 100= 600 mcg/cc Dop
600mcg/cc divided by 0.5kg= 1,200 mcg/kg/cc
1,200mcg/kg/cc divided by 60 minutes= 20mcg/kg/min per 1cc
Dosages range from 2mcg/kg/min to 20mcg/kg/min. I suppose some places do as low as 1mcg/kg/min but I was told that that dose really doesn't do anything. Once you get down to 4mcg/kg/min it's basically for renal perfusion and really doesn't do much for the systemic blood pressure.
Our docs vary in how they write for infusion changes. Some write the IV rate and others write how many mcg/kg/min they want. Usually they write the # mcg because that way they don't have to worry about whether the pharmacy has sent standard or double concentrated dopamine or dobutamine.
Last edit by Gompers on Dec 27, '03