First four semesters (spring, summer, fall, spring) you can pretty much plan on having class or clinical 4 days a week. I generally had one day "off" (i.e. studying) during the week. Some courses are online or hybrid online/in-class, so that gives you a little more schedule flexibility. The last two semesters are part time and I was able to work full-time as a nurse during that time.
I am considering doing the post-masters certificate to become an FNP at UNH, but with job changes I've put that plan on hold for a bit. I do know of other DEMNs in the post-masters program, though, and they are doing well.