Re: propofol infusion syndrome
In my opinion the benefits of this drug outweigh the risks in many cases. Some of this research is pretty poor in my opinion. You could potentially pick this to death if you had to. One study metions that to date there are only 14 known cases of it, another lists some very broad symptoms that could be associated with many, many other conditions and another study even lists this as being very rare. I do agree that it definately has renal risks and increased risk of infection. We see rhabdo a lot with it when ran at higher rates for over 48 hours. Our facility monitors labs for this and makes an attempt to switch to our "sedation protocol" to minimize its use. Our sedation protocol involves fentanyl drips, versed drips, ativan, morphine and about anything else we need.
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