nimodipine

Don't crush enteric-coated tabs!

I've never seen nimotop come in an enteric coated tab. Are you sure you're talking about nimodipine?

They were capsules when I was in neuro. We got the med out of the little capsule whatever way seemed most reasonable at the time. Some of the nurses put them in hot water and let the geltine capsule dissolve and some of us stuck the capsule with a needle and squirted out the liquid.

They had to be given religiously within minutes of the time scheduled dose time.

Love

Dennie

In our unit, giving nimotop is usually by way of mouth or NG because as you know, mot aneurysm patients are very very lethargic and rarely alert at first. If they can't swallow it and don't have an NG, I squirt the contents of the soft capsule into a syringe and into their mouth. Its very important for neuro pts to get this med as it reduces incidence of venospasm post-op which is a horrible complication of aneurysm clipping/coils

Rails - I'll bet you're talking about NIFEDIPINE!!! That comes in a coated tab.

Nimotop is an oily liquid that comes in a thick gelatine capsule. erezebet and I have given it to aneurism patients and it's an effective but very expensive drug that HAS to be given Q 4 hours - not Q3 hours and 30 minutes or Q3 hours and 45 minutes or 4 hours and 10 minutes....

I know that sometimes drug companies give the same meds different names in different countries, but I am pretty sure that we're talking about two different meds. They're both calcium channel blockers, though.

But I stand by my original statement that you should *Never* crush up enteric coated meds. Some of those enteric coatings are the time release factor. If you break up the enteric coating, then you release meds immediately that are supposed to be released gradually over time.

Love

Dennie

Don't Crush that tablet!

Crushing enteric-coated tablets can jeopardize the drug's stability.

Crushing Sublingual tablets can make the drug unusable or ineffective.

Any drug formulation that claims to be extended release should not be crushed.

Consider compatibility of medications with enteral products before administering them together.

Some alternatives to crushing tablets or capsules include using a suppository or liquid formulation of the same medication, either commercially available or extemporaneously compounded. If the desired dosage formulation is not available from a pharmaceutical manufacturer and compounding is not feasible, recommend a therapeutic alternative that is available in an acceptable dosage formulation.

(Ref.: American Pharmacy. May '94 Vol. NS34, NO. 5. P.57-58)


I'd discuss this issue with the Pharmacy...

We use Nimodipine (NIMOTOP) in my Neuro Unit in the UK. It is definitely enteric coated and it is crushed for patients who are unable to take oral medication. We have discussed the effects with our Clinical Pharmacy Specialist and he says that it contravenes the license and should not be done.!! Our medics insist that we carry on the present practice. They don't say where they will be when litigation commences! They also decline to give written orders for the practice... still we outnunmber them and we have sufficient witnesses on our side. ). Our pharmacy are able to produce it in liquid form but the Pharmaceutical company refuse to grant us a license to do so. Funny old world?

Jonty45

"We have discussed the effects with our Clinical Pharmacy Specialist and he says that it contravenes the license and should not be done.!! Our medics insist that we carry on the present practice. They don't say where they will be when litigation commences! "

Uhhh what part of "NO" do your medics not understand? Ask these "medics" for the research that condones using this medication outside it's prescribed limitations. If you're unable to stand up to them yourself, tell your Supervisor, Manager, Pharmacy Manager... someone who will step up to the plate on this issue.

Particularly since you KNOW this not to be good nursing/medicine... your butt is in a sling if there is ever litigation because of this. It's your license, protect it.

i love this neuro stuff... no neuro unit where i work