I love the Nook because it's compatible with more formats. HOWEVER, you'll probably find that the ereaders are not a particularly good solution for reference materials. Note taking is a known deficiency, and the search features are so-so. You also will not be able to find most of the textbooks available for ereaders. Ereaders are fantastic for any book that's almost all (if not all) text with no tables, pictures, etc. that you will read from beginning to end. They're not quite there yet for other applications.