DISCLAIMER - I'm only speaking of my own experience as a male working with women in health care for the past 20 years, after having worked in factory-type settings with men:
No question, working in a predominantly female environment is much different than working with men and all the guys I've worked with in health care in the past 20 years agree. Things are taken a little more seriously; whereas guys tend to joke around and be much more shallow as far as working relationships go, the women take things more seriously and relationships are deeper and more emotional. When the working relationships are good, things are very good. When the working relationships go south, WATCH OUT - lines are drawn and grudges are held for years. Guys seem to shrug things off easier, but women take everything personal. Cat fighting? Yep. Also, they can be very clique and boundaries between them like electric fences.
I'm not being stereotypical, I'm just calling 'em as I sees 'em. I think it's much easier having been married to one of these creatures for so long - the experience gleaned from living with one so long has helped to make working with them much easier
Joking aside, personalities vary, and some PEOPLE, men & women, can be easier or harder to work with, that's a given. I am the type that just finds it easier to get along with everybody, and it's worked for me - I can't remember the last time I've had a heated exchange with any of my coworkers...it's been at leat a dozen years. If you're a good worker, a team player, then it's much easier to earn respect, and that is the key. Give and take; goes both ways.
Oh, also...tiptoe into work and hope and pray they aren't all having their periods at the same time...okay, I couldn't resist
As for difficulties with management, I don't think it's any different than any other large organization, although it may differ slightly between unionized and non-unionized workplaces. Much of the infighting can be attributed to all the changes in health care: funding, service delivery, government, etc, perhaps more changes than in other sectors.
Morale? Tough to generalize, but again, much has to do with what I stated above.