IV Phenergan - page 3

Has anyone experienced problems with IV Phenergan 25 mg. We are currently having trouble administering it to any one. It seems like everyone has respiratory depression with this drug. We have had a... Read More

  1. by   canoehead
    I think a dose of Zofran is over $200 and Phenergan is $1-2.
  2. by   susanmary
    Routinely give 4 mg Zofran diluted in 50 cc normal saline for nausea/vomiting post-operatively. Have had orders to give up to 8 mg Zofran at one time, but have found that if 4 doesn't work - then 8 doesn't work. In my experience, anyway. Rarely, have given phenergan -- have given both the IV/IM routes with no noted side effects. Agree that when I'm in the hospital, I want Zofran FIRST.
  3. by   deespoohbear
    Originally posted by canoehead
    I think a dose of Zofran is over $200 and Phenergan is $1-2.
    If I am heaving, I am willing to pay about anything to stop it. I hate to throw up and will do about anything to stop it!!
  4. by   sara2
    I have a lot of respect for phenergan iv. In my early days of med surg nursing I gave a 99 year old hip surgery patient 25 mg Iv. It should have been given IM according to the order. Almost instantly she went into CHF. Had it not been for an agressive charge nurse who called the patient's medical doctor and demanded a huge dose of Lasix, she would have probably been a goner that night. I was only a year into nursing at that time and almost got out of it because of that but the charge nurse encouraged me to stick with it. That was more than 10 years ago and then you never saw an order for less than 25 mg phenergan iv. Now, almost all our orders are for 6.25 or 12.5 mg. When I have an order for 25 mg iv, I now titrate it. By the way, I kept track of that patient and she lived to a ripe old age of 105.
  5. by   kae rn
    I have worked years as a peds nurse on med/surg, ortho, and outpt. floors. I would hesitate to give phenergan IV on a child. A teenager, maybe. I prefer the pr route, even though parents and kids cringe. Just less side effects. I think Zofran works well if given intra-op.
  6. by   deespoohbear
    I hear that Phenergan supp burns like fire. Anyone with any experience with that? If I have both ends going, I doubt if I want to do a pr with a medication that stings!!
  7. by   LilgirlRN
    Just dilute it and give it slowly. Use 6.25-12.5 with the elderly. Hate inapsine, it doesn't work. We use vistaril IM a lot too. Use Zofran for hyperemesis.
  8. by   AHarri66
    We've had a few cases of respiratory depression and unresponsiveness with Phergan over the past year, so we have a new policy for administration. We dilute the dose in 50cc of D5 or NS and hang it over 15 minutes. No adverse effects from that yet. I have seen Zofran used more frequently now, too, and I have to admit, I'm much more comfortable giving that.
  9. by   AHarri66
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    Last edit by AHarri66 on Jan 2, '03
  10. by   ShandyLynnRN
    I had to use phenergan PR once, and didn't notice the burning. Ofcourse, I was knocked out cold as a side effect....maybe I didn't notice????
  11. by   bossynurse
    We too autosub phenergan for compazine due to shortage. I hate giving it i.v. I checked on this guy 5-10 minutes after dose given he couldn't keep his eyes open. I asked him his name, he incoherenty responded. I layed him down checked his v/s. (good)
    and he promptly sawed logs for hours. coworker had a pt pass out in bathroom after phenergan. A 30 y/o fresh p/o coded after a dose. I tell any Doc who tries to give me I.V.phenergan orders that I'm not comfortable with it and they order something else.

    We too use zofran on p/o pts but its worthless. Reglan is given to just about everyone. We use tigan i.m. or p.r. and compazine p.r.
  12. by   duckie
    This post just made my stomach hit my throat!!!!! Due to my various illnesses, in the past 2 months, I have been in the position of receiving IV Phenergan 4 times. Thankfully, I'm obviously not affected by it BUT holy crap, now you got me all paranoid!!!! The last trip to the ER, the one where the Pharmacy OD'd me on Bactim DS, I had it 2 times in 3 hours because they couldn't stop the vomiting and dry heaves. I guess sometimes the cure can kill faster than the ailment!!!!

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