I've lived in Louisiana for the past 10 years, in New Orleans, in a small, rural town near the Texas border, and now in Lake Charles, which is a city of approximately 70,000 surrounded by small, rural communities.
Earlier posts are correct that pay here is much lower than other states, particularly in the north. Nurses in this area often move to Texas, particularly Houston, as the hourly rate increases $8-15/hour. Another consideration is nurse/patient ratios. In the large hospitals in my area, the nurse / patient ratio is generally 1:6-7. On my unit, we can have as many as 8 patients before the staffing matrix calls for another nurse.
Other considerations about the rural south: very religious, conservative politically, poor public education system, widespread poverty, and it's HOT. Regarding rural communities specifically, there's a real need for nurses, and your work could be very rewarding. People here are polite and friendly but a little suspicious of outsiders. Most people where I now live have been in this area for at least 4-5 generations, and as soon as they hear your name, they immediately try to make connections to which particularly family in what exact local town.
I love living in southern Louisiana, and encourage you to come visit. There's delicious food - Cajun, creole, seafood - and wonderful music... quite a unique culture.