renal perfusion question

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    hello I'm studying about dopamine receptors in the periphery located in the kidney, it says that it enhances renal perfusion by dilation of kidney vasculature.

    My question is what exactly is renal perfusion? I know it increases O2, and RBC production, but still don't understand what it does or how it relates to medications involved in this process like drugs for parkinson's disease for example.
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  5. 0
    Quote from little margarita
    hello I'm studying about dopamine receptors in the periphery located in the kidney, it says that it enhances renal perfusion by dilation of kidney vasculature.

    My question is what exactly is renal perfusion? I know it increases O2, and RBC production, but still don't understand what it does or how it relates to medications involved in this process like drugs for parkinson's disease for example.
    Perfusion = blood flow. Dopamine, as I recall, in low dosages is supposed to increase blood flow to the kidneys via vasodilation of the arteries supplying the kidneys. To answer your second question, the dopamine that is used in renal patients doesn't have anything to do with the dopaminergic drugs used in treating parkinsons because dopamine doesn't cross the BBB so you can't give it directly for pt's with parkinsons..you gotta give them some kind of precursor drug that can cross the bbb and be converted to dopamine.
  6. 0
    How does perfusion exactly work (even without the drug) does it increase blood flow to organs when the vasodilatation happens?
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    Perfusion is a fancy word for blood flow. It is the same thing! So, in case of vasodilation you have increased perfusion or incresed blood flow.
  8. 0
    Perfusion is kept up by the body with normal blood pressures with different processes.
    What is Perfusion?

    When was your book written? There is plenty of evidence out there against the use of dopamine to increase renal profusion.
  9. 0
    If you have adequate perfusion to your kidneys, that means you have adequate blood flow. Dopamine, in low doses (called "low dose dopa" or "renal dose dopa") helps improve renal perfusion. Those doses are typically 1 - 3 mcg/kg/min. Dopamine at higher doses, however, loses that renal effect.
  10. 0
    Quote from little margarita
    hello I'm studying about dopamine receptors in the periphery located in the kidney, it says that it enhances renal perfusion by dilation of kidney vasculature.

    My question is what exactly is renal perfusion? I know it increases O2, and RBC production, but still don't understand what it does or how it relates to medications involved in this process like drugs for parkinson's disease for example.
    Every organ needs blood flow (i.e. perfusion) to function properly. The kidney is very sensitive to lack of perfusion, and damage can occure quickly if there is not sufficient perfusion. In fact, if the perfusion is not satisfactory, the kidney can 'simulate' a rise in BP (see the renin-angiotensin-aldosterone axis). I'm not sure what you mean by 'increases O2.' There is no direct link between renal perfusion and Parkinson's other than Parkinson's druge contain dopamine, but this not the same as giving dopamine to increase renal perfusion.


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