Pharm problem help!?

  1. Nafcil IM requires the additional of 6.6 ml of sterile water for reconstitution. The reconstituted solution has a dosage strength of 250 mg per ml. If a
    350 mg dosage is ordered, how many ml will you give
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  2. 5 Comments

  3. by   chare
    Why don't you show us what you have done so far? This will better allow us to help you if we see where you are having problems.
  4. by   btf4
    "X"ML= 350mg/1* 1/250mg * 6.6= 2310/250= 9.24ML
  5. by   chare
    Quote from btf4
    "X"ML= 350mg/1* 1/250mg * 6.6= 2310/250= 9.24ML
    You are trying to include way too much information in your problem. When you work this type of problem you are often provided much more information than you need; therefore you need to determine what information you need to solve this.

    From the information provided in your original post, what are you being asked to solve, and of the information provided, what do you think you are going to need?
    Quote from btf4
    Nafcil IM requires the additional of 6.6 ml of sterile water for reconstitution. The reconstituted solution has a dosage strength of 250 mg per ml. If a
    350 mg dosage is ordered, how many ml will you give
  6. by   btf4
    im being asked for how many ml to give, so i should not include the 6.6ml in the equation? so "X"ml=350mg * 1/250mg= 1.4ml?
  7. by   chare
    Quote from btf4
    im being asked for how many ml to give, so i should not include the 6.6ml in the equation? so "X"ml=350mg * 1/250mg= 1.4ml?
    Yes, 1.4 mL is correct.

    As you were provided the concentration after dilution (350 mg/mL) you do not need to include the 6.6 mL diluent volume. For most, if not all medications that you reconstitute, the volume of diluent (6.6 mL) to use, and the final concentration (350 mg/mL) will be provided on the vial or in the package insert.

    Also, for this you could have used the D/H * V formula, where D equal the dose to administer, H equal the concentration that you have, and V equal the volume for H.

    Good job!

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