help with pharm question please/thank you

  1. The order is for 0.1 g subcutaneous. The label says that the vial contains 500mg of dry powder. Which dilution is most appropriate?

    Dilute with 2.3 ml for a concentration of 200 mg/ml
    Dilute with 5.8 ml for a concentration of 500 mg / 6ml
    Dilute with 9.8 ml for a concentration of 200 mg/ 4ml

    a. The nurse should dilute with _____________________ ml.

    b. How many ml will the nurse give the patient_________________ml
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  2. 19 Comments

  3. by   chare
    As with your other post, why don't you show us what you have done so far?
  4. by   btf4
    (first) "X"ml=200mg * 2.3ml/500mg= 0.92 ml
    (second) i crossed multiplied because i am not sure how to find "x" if there is already a number there, so i did. 500mg/6ml * 5.8ml/500mg= 2900/3000= 0.97ml
    (third) 500mg/9.8ml * 4ml/200mg= 2000/1960= 1.0ml
  5. by   chare
    Quote from btf4
    (first) "X"ml=200mg * 2.3ml/500mg= 0.92 ml
    (second) i crossed multiplied because i am not sure how to find "x" if there is already a number there, so i did. 500mg/6ml * 5.8ml/500mg= 2900/3000= 0.97ml
    (third) 500mg/9.8ml * 4ml/200mg= 2000/1960= 1.0ml
    As with your other problem, you are trying to use all of the data provided, and that is not necessary.

    Referring to the original problem, what exactly are you being asked to determine?
    Quote from btf4
    The order is for 0.1 g subcutaneous. The label says that the vial contains 500mg of dry powder. Which dilution is most appropriate?

    Dilute with 2.3 ml for a concentration of 200 mg/ml
    Dilute with 5.8 ml for a concentration of 500 mg / 6ml
    Dilute with 9.8 ml for a concentration of 200 mg/ 4ml

    a. The nurse should dilute with _____________________ ml.

    b. How many ml will the nurse give the patient_________________ml
  6. by   btf4
    which dilution is most appropriate and how much ml should i administer for the corresponding ml
  7. by   chare
    Quote from btf4
    which dilution is most appropriate and how much ml should i administer for the corresponding ml
    Exactly. so what do you think you should do first to solve this?
  8. by   btf4
    I'm not completely sure with this one, i tried doing this.
    (first) 500mg * ml/200mg= 2.5 ml
    (second) 500mg * 6ml/500mg= 6ml
    (third) 500mg * 4ml/200mg= 10ml
  9. by   chare
    Forget borh the total dose in the vial (500 mg) as well as the diluent volumes provided (2.3 mL, 5.8 mL, and 9.8 mL). As with your other post, medicationsnthatnare reconstituted willnprivide you a diluent volume, and the final concentration that this results in. Sometimes this will be provided as x mg per 1 mL. Other times, they will provide the concentrion as x mg in y mL; this is what you have in your problem. For example, if you reconstitute the vial with 9.8 mL of sterile H2O, this results in a final concentration of 200 mg/4 mL.

    What do you think you should do now? You van wirk this the in the same manner you did inbyour other post.

    ETA: Pardon the delay, and please forgive any typos as I'm posting on my phone.
  10. by   btf4
    like this? "X"ml= 0.1G * 1000mg/1g * 1ml/200mg= 0.5 ml?
  11. by   chare
    Quote from btf4
    like this? "X"ml= 0.1G * 1000mg/1g * 1ml/200mg= 0.5 ml?
    Yes, and again, good job. Not exactly how I would have worked it, but this method works for you.

    A skill that you need to develop is being able to read the problem, and determine what you need. Sometimes it will be fairly straight forward, and other times it will be somewhat mors comploxated as there mighr be a considerable amount of distracting information. Regardless of how much onformation providsd, the first step should always be to determine exactly what you are solving, and then determine what information that you need.
  12. by   btf4
    and for the second part it would be like this? because "X" has a number which is 6 so..
    "X"ml= 0.1g * 1000mg/1g * 6ml/500mg = 1.2ml?
  13. by   chare
    Quote from btf4
    and for the second part it would be like this? because "X" has a number which is 6 so..
    "X"ml= 0.1g * 1000mg/1g * 6ml/500mg = 1.2ml?
    I might have not been following as closely as I could have.

    You have an order to deliver a 0.1 g dose of medication via subcutaneous injection. The medication in question can be reconstituted to one of three final concentrations: 200 mg/mL, 500 mg/6mL, and 200 mg/4 mL. Which concentration do you think is most appropriate?
  14. by   btf4
    the 200mg/ml because 1ml is the max administration for an adult male subcutaneous. the first concentration is 0.5 ml which is below the range, the second concentration is too high because of the equation i just posted which equaled to 1.2ml which is already above the max concentration allowed subcutaneously

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