which is CK-MB?

  1. 0
    which is correct for CK-MB?

    (these are from acronym finder):

    CKMB P-creatine kinase myocardial band
    CKMB creatin kinase isoenzyme MB
    CKMB creatine kinase isoenzyme MB
    CKMB creatine kinase isoenzyme MB
    CKMB creatine kinase MB fraction
    CKMB creatine kinase MB isoenzyme
    CKMB creatine kinase/MB isoenzyme
    CKMB creatine phosphokinase MB
    CKMB creatinine kinase MB isoenzyme
    CKMB Creatine Kinase Myocardial Band

    there is also Creatinine Kinase, Muscle & Brain listed for CK-MB

    which is it?
    The topic is MI.

    thankyou
    ******************
    Last edit by GingerSue on May 29, '07
  2. 5 Comments so far...

  3. 0
    CK-BB = brain
    CK-MM = muscle
    CK-MB = cardiac tissue

    I am not quite sure what you are attempting to ask.
  4. 0
    what does CK-MB stand for?
  5. 0
    Quote from GingerSue
    what does CK-MB stand for?
    Creatine kinase myocardial band as for your abbreviations on your first post they are all correct.
  6. 0
    Creatinine Kinase- Myocardial Band. It's what I thought but a simple yahoo search confirmed it on the first page. CK is an enzyme released from muscles when they are damaged or die. There are several sub-categories that will help distinguish between skeletal muscle damage and cardiac muscle damage. MB is the important one to indicate heart damage.


    And it wouldn't be incorrect to include the word isoenzyme when describing CK-MB. A patient can have an elevated CK but if the MB portion is normal it's less likely (though not definitive) they have heart damage. They can have a normal CK but the MB portion will be elevated and is indicative of heart damage. This can get really involved; let us know if you need to know more.
  7. 0
    In clinicals last year I had a patient that had several broken ribs and bruising over 1/3 of his torso from a four-wheeler accident that resulted in him hitting a tree. His CK-MB was fine but his CK-MM was through the roof. This indicated that though he had massive smooth muscle damage, his heart probably had no trauma. Troponin I and Myoglobin are two other tests for MI. The all have different time ranges though. For instance a myoglobin can indicate an MI but may not be appropriate if someone had chest pains on Friday and finally came in on Sunday, still feeling bad, because Myoglobin levels drop off after 24 hours, whereas Troponin I and CK-MB last longer after an event. myoglobin can also indicate skeletal muscle damage too.


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