sandostatin injection times

  1. I need some comments regarding admin of sandostatin (octreotide injection), not the long-acting.

    If you give it in your workplace, what times is it usually given? We are having a debate in our palliative care. The day nurses schedule the a.m. dose for 6 a.m. but some of the night nurses are reluctant to wake patients for this one med if there are no others, so they would prefer to see it changed to 8 a.m., when there is a much higher likelihood of the patient being awake.

    Thanks,
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  2. 16 Comments

  3. by   ginger58
    We usually give it between 09 and 1400. I definitely wouldn't wake someone up to give most anything.
  4. by   Rabid Badger
    I would not wake a palliative patient at 6 am. Especially for a injection that could be easily scheduled later without undue harm or side effects to the patient.
  5. by   clemmm78
    Thank you to both of you for responding. This is a running battle the night staff is having with the day staff. They are insisting that it is vital that the patient receive it to fight of early am nausea symptoms in combination with early PRN Gravol (dimenihydrinate) but they are *sleeping*. Morning care only begins when they wake up. They set their own schedules.

    I'm very frustrated.
  6. by   Rabid Badger
    Why can't you give it sc via a sc line to avoid waking and poking the patient?
  7. by   clemmm78
    we do give it that way. But 9 times out of 10, the patient wakes up because we have to get to the butterfly which is on the arm, the chest or the leg.
  8. by   Rabid Badger
    Well honestly in that case I would give it at 6 am, so the patient does not wake up for washing/breakfast/etc nauseated. Its a bit different to wake a palliative patient at 6 am for a poke versus a slight touch of the hand, gentle awakening and soothing back to sleep as you give a med via sc line. When I give abx at 6 am, 99% of the time the patient rouses enough to see that I am an there and am not the boogeyman, and they fall back to sleep.

    I think in this case the beneifts of giving the med early outweigh the cons.
  9. by   clemmm78
    I understand your point, however, morning care in our place begins *late*. Even if they were woken at 8, they still would have plenty of time for washing up, breakfast, whatever. baths, are never done before breakfast, and breakfast is whenever the patient wants it, starting only at 9:30.
  10. by   Rabid Badger
    I guess what I am saying is that as a patient, I'd rather be accidentally woken at 6 am to be given my anti-nausea meds in a non-painful manner than to wake up on my own at 8 feeling nauseated and heaving. My need to be nausea free is more important to me than possibly being woken by someone accessing my line. Therefore the benefits outweigh the cons to me as a patient. And so that is how I would approach the situation as the nurse.
  11. by   clemmm78
    Point is taken. Thanks. That's why I asked!
  12. by   Rabid Badger
    No problem. Hope that was helpful.
  13. by   ginger58
    Marijke, Don't back off so fast. Here's the peak, half life, etc. I found:


    The elimination of octreotide from plasma had an apparent half-life of 1.7 to 1.9 hours compared with 1-3 minutes with the natural hormone. The duration of action of Sandostatin (octreotide acetate) is variable but extends up to 12 hours depending upon the type of tumor. About 32% of the dose is excreted unchanged into the urine. In an elderly population, dose adjustments may be necessary due to a significant increase in the half-life (46%) and a significant decrease in the clearance (26%) of the drug."
    So, it's quick acting, has a T1/2 of <2 hours and can work for 12 hours. We really don't use it for n/v but diarrhea.
  14. by   taramayrn
    I believe we normally give this drug at 0800. I certainly wouldn't give it at 0600 (unless the pt requests it at that time, etc) and wake the pt up unnecessarily.
    We normally do not use this drug for n/v or diarrhea but to suppress the growth hormone therefore hopefully decreasing tumor growth.
    In this case, I believe it is dependant on the pt. If the pt is constantly c/o nausea (and if that is what the drug is being given for) then I would, as a previous poster mentioned, gently give the medication and offer analgesic and repostioning at that time as well. Also a nice warm blanket to help them resettle. Consult the pt - what would they prefer? Do they mind getting woken for the medication or would they prefer to wait until they wake?
    Last edit by taramayrn on Feb 15, '07

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