i found this article very interesting and thought i'd share it. it was based on a study that was published in the dec 06 issue of 'journal of immunology.' unfortunately when you click on the link to read the actual study you only get the abstract version. hope the link works, i've never tried to post a link here before.
"with flu-shot season in full swing and widespread anticipation of the hpv vaccine to prevent cervical cancer, a new university of rochester study suggests that using common painkillers around the time of vaccination might not be a good idea.
researchers showed that certain nonsteroidal anti-inflammatory drugs (nsaids), also known as cyclooxygenase inhibitors, react with the immune system in such a way that might reduce the effectiveness of vaccines.
the research has widespread implications: study authors report that an estimated 50 to 70 percent of americans use nsaids for relief from pain and inflammation, even though nsaids blunt the body's natural response to infection and may prolong it......."