I have a BS in Agricultural Science and will begin my clinicals for an ASN program this coming fall.
Check to see what credits you have from your first degree that might be applied towards your RN, whether it be BSN or ASN. My school will allow you to transfer classes that have been completed within the past 10 years.
Then, see if any of your local schools offer an Evening/Weekend option or any other program for adult students. With the shortage many schools are offering special options for adult students. The school I am attending is an Evening/Weekend option where all classes are held in the evenings during the week and clinicals are held on Saturdays, so, if you have to work a full time, regular job, class will not interfere with that.
Which ever route you go, I would suggest that you take all of your pre-and co-requisites before you start taking your "Nursing" classes and clinicals. It will still be tough, don't get me wrong, but it will be less stressful and you'll have more time to work, study, etc. if those are out of the way.
A lot of people on this board have gone through Nursing School and worked full time plus many raised their families during this time too. It can be done but it is a personal choice and is dependent on how hard you are willing to work, what types of things you have on your plate (house, spouse, kids, $$, etc.) and how well you are able to cope with everything. For me, I have decided that I will stick it out and try to work while in my first year of school but after that, I'll try to find a part time or less than part time job as an intern or PCT during my second year and make do with whatever money I have.