Go onto the unit with a helpful and humble attitude. At the same time, give yourself credit for what you do know. This is a hard balance to strike. If you act like you know it all, they'll all wait for your first screw up. If you don't make one decision alone, people look at you like a millstone. Try to strike the balance. Do more listening than talking. Try your very best, but don't expect constant perfection of yourself.
If you find a congenial new grad or two or three that you can be friends with, this is great. I had many of my classmates around me as a new grad since I worked in the hospital I studied in and it was invaluable personal support. If not, keep in contact with nursing school
buddies for support. With a little luck you will have a GREAT assigned or natural mentor. Again, we had lots of natural mentors among us, but I think this is more of a rarity than it used to be. Help others, including your aide, LPN, when you can so that they might help you when they can. Give your aide LPN good feed back when they let you know helpful observations (high, low bp's, low or high urine op's, etc). This helps for when they DON"T tell you things you needed to know.
Have a plan of attack for organization but don't be surprised if events conspire to change it. Mine was report (who is your high priority patient?), review charts quickly for new orders, progress notes, and get med admin times and tx's on cheat sheet. See my highest priority patients first (i did this as I reviewed charts, MARs, TX's). Do assessments on highest priorities patients and then the rest. start meds. (I usually was a 3-11 person). The shift you work will change this. Sometimes, I just flew through the charts to get med admin and tx's times down but if you are getting a new admit or come onto an unstable patient, you see your highest priority patients first. When the exceptions happen, you may assess patients when you give them their 6 o'clock meds. (We all hate that, but you've got to let your priorities drive your time allotment). You will soon get a sense of typical med admin times on your unit. Where I worked we tried very hard not to schedule meds (expect for antiobiotics if indicated) at 4 pm or even 5 pm, but you were sure to have a boatload of 6 pm's. You get a sense of the rhythm of the unit, even to when the trays come, but __it just takes time___.
I hate to say this, but expect to go home drained at first. It's just so new and it seems like every decision you make is so big, but over time, you start to see some decisions that are like decisions you made before, so you don't feel so blind sided by them.
Good luck. Be patient with yourself. Time improves things and nothing can remove first day jitters. It just means you realize how important the job is and you care about it.