Metabolife - page 3

This is an herbal based weight loss pill. Anybody else seeing patients with severe adverse reactions?... Read More

  1. by   teeituptom
    Howdy yall
    from deep in the heat of texas

    Good ole metabolife and other ephedra products. You can call it job security. Ive seen people who have had MIs, CVAs, TIAs on that stuff. Not even compared to those who come in with palpitations, anxiety disorders, hyperventilation, and other personality disorders exacerbated by this ****. Sometimes makes it hard to feel compassion for some of these idiots.
    Then you combine this with all the others who come in with substance abuse, whether its alcohol, cannabis or other street drugs. Also those who abuse prescribed meds, pain meds, antidepressants, and others. Like I said you can call thet job security.
    Plus they opened a ice and skating palace down the road. People hit with hockey pucks in the face, or sticked, or whatever. plus they have ramps for inline skating and skateboarding and such, that also gives us a lot of business too. One of the Orthos has his office right across the street from it, good thinking.




    doo wah ditty
  2. by   Peeps Mcarthur
    Very curious,

    I have been taking Ephedra products of one kind or another for about 12 years now with none of these side effects. Sometimes I take additional Ephedra with my Caffeine/Ephedrine combination supplements if I need the energy boost to last. I also drink coffee from my french press most mornings.

    I recently had my bp checked @ 130/90 so I see none of your specters of Ephedra looming in the shadows, but I have found that persons who supposedly don't tolerate Ephedra without palpations and diaphoresis also can't tolerate drinking just one cup of coffee by itself. Amazingly, the same palpations and diaphoresis are present with just a cup of coffee yet,these people are actively blaming the Ephedra in these products.

    It's all just media hype until it can be shown with something more than just anecdotal report,but that poor little bronchodialator Ephedra will shoulder the blame until something sexier comes along.
  3. by   preciousnurse
    No I have never tried the bad stuff, hell I have never drank one beer or smoked one cigarette and I am 25
  4. by   zudy
    I have had pts in the ER have seizures ( with no history of a seizure disorder) after taking this garbage. Enough said.
  5. by   emrettig
    Peeps,
    Do you know that 90 diastolic pressure qualifies as hypertensive. If you showed up at a blood pressure screening at my church I would have to give you a warning.

    Keep the Faith,
    Eileen
  6. by   mario_ragucci
    Does anyone know what happens chemicals like ephedra, or caffeine, once it enters the body via stomach epithelium? Does your body changeit into something else? Basically, what other chemicals are involved in metabolism ephedra, and then how is it excreted (kidneys)? Do these oral drugs/meds enter your blood/heart/lungs via the stomach or duodenum?

    Now I am confused and realize I don't know jack about meds because i can't explain what happens after you swallow it? I am sorry to ask this question, and am a dunce. Please do not blow me away with super-hardcore vocabulary :-(
  7. by   twells
    I think our psych center has seen a few people with destabilized conditions when they were on metabolife. If it can bring out the psychosis in you, it's probably not very good for you.

    I agree with the diet and exercise advice (skipping sugar in the evening usually makes you feel better in teh morning).
  8. by   Youda
    Originally posted by mario_ragucci
    Does anyone know what happens chemicals like ephedra, or caffeine, once it enters the body via stomach epithelium? Does your body changeit into something else? Basically, what other chemicals are involved in metabolism ephedra, and then how is it excreted (kidneys)? Do these oral drugs/meds enter your blood/heart/lungs via the stomach or duodenum?

    Now I am confused and realize I don't know jack about meds because i can't explain what happens after you swallow it? I am sorry to ask this question, and am a dunce. Please do not blow me away with super-hardcore vocabulary :-(
    Mario, these are far from dunce-type questions! I've read your posts before, and they are very well thought out. You have a keen mind that is searching to understand these things. That's refreshing to see! Wish we could sit down and talk about these things for a few days! (It isn't like there are large numbers of people who want to know!)

    The chemical reactions are too involved for me to go into them here on a bulletin board, what happens after you swallow the pill, ephedra, whatever. So, I'd really recommend that you find a book on ORGANIC CHEMISTRY or MICROBIOLOGY at the beginning level. The kinds of questions you ask on the various topics at allnurses, I think you'd find what happens and why a very interesting topic, and it would give you a good basis to understand these kinds of reactions.
  9. by   mario_ragucci
    Thank you Youda - Often times I like to take what I am thinking about at face value, that is, how it can be imagined. I know that chemicals can be in solid, gas or liquid forms. So, when ephedra liquid gets to your stomach, does it get metabolised like, say, a glass of orange juice does? Does your body think it's a sugar, and then raise insulin levels? Can ephedra participate in the Kreb cycle, or electron transport.sys, or does your body make it into glucose?
    How come when you swallow pill meds, they don't slide all the way down to your cardiac spincter and pass into your duodenum whole? Do they get stuck on your stomach epitilium and disolve always? So often I see PT's swallow meds and I think, "what does their stomach look like?" If you place a pill in a glass of water, it will float to the bottom in tact. If you swallowed a pill with a 12oz glass of water, wouldn't it too drop right to the bottom part of your stomach, and rest on the cardiac spincter?
    I know this is a thread about metobolife, but this is also interesting, re: how metabolife metabolises.
  10. by   Peeps Mcarthur
    Isn't ephedrine the active metabolite of Ephedra?

    Isn't that in OTC cold remedies?

    I'm not saying that Ephedra is "safe",but I am looking at it objectively. How can we link Ephedra to all of this objective data without an objective measurement?
    It's too easy to r/o other causes and blame Ephedra for my mild hypertension. Little do you know................

    Sedentary lifestyle
    40 lbs overweight
    41 y/o
    Male
    Poor diet

    I don't think that entered into the criteria,just that "oh wow,Ephedra is causing this person pressure changes"

    Right?

    I don't believe everything the FDA tells me either. Has everyone forgotten that they approved Phen-Phen? How can they have credibility?
  11. by   Youda
    Originally posted by mario_ragucci
    So, when ephedra liquid gets to your stomach, does it get metabolised like, say, a glass of orange juice does? Does your body think it's a sugar, and then raise insulin levels? Can ephedra participate in the Kreb cycle, or electron transport.sys, or does your body make it into glucose? (snip)

    I know this is a thread about metobolife, but this is also interesting, re: how metabolife metabolises.

    No, it wouldn't get metabolized like glucose because it is made of different molecules. To answer another post, ephedra, as I undertstand it, contains ephedrine and the analogs of ephedrine, pseudoephedrine and norpseudoephedrine, as well as other chemicals. You folks had me looking over the internet for some information, and I found this wonderful discussion of the extraction and synthesis of ephedra. Mario, check out the chemical references at the bottom of the page to give you your answers about what chemical groups the ephedra would breakdown into.

    http://www.ephedra.demon.nl/stories/chemical.htm

    The side effects would be caused primarily by ephedrine's stimulation of cardiac, bronchial, neurological, etc., systems with its concurrent vasoconstriction. Strolling around the internet, I'm also seeing drug interaction warnings that would, no doubt, contribute to any side effects (beta blockers, mao inhibitors, etc.)

    OK, Mario, that's all the free homework you're gonna get out of me on this!
  12. by   flowerchild
    So that's what caused it! I'm so glad to know that a couple of years ago, I was drinking those energy/herbal drinks, ended up lying in bed with s/s of stroke. Numb on one side of my body, including my face, drooling, and was having palpitations. I thought I was a goner for sure! I'm young enough, healthy, not overweight, great BP, etc. Eat right, drink plenty of water, and here I was thinking I was having a stroke. I never put two and two together till I read these replies. Now I know it was those stupid drinks I thought were so good for me! You won't catch me buying those anymore nor would I ever take Metabolife or any other product with ephedra. Oh, I and btw, I drink caffeine drinks on a regular basis (in moderation, usually) and have never had any reaction even remotely similar to what the ephedra did to me, so I for one don't believe that ephedra is the same as caffiene.
    The risks are real imo if you decide to take this stuff. You know how we keep hearing about these ball players, high schoolers, etc. just dropping dead on the court or feild while they are playing? Makes me wonder if the cause is these OTC energy drinks that caused it? It makes no sense to me that a perfectly healthy 16 y/o, in top form and condition, just keels over, without a reason.
  13. by   Youda
    Originally posted by flowerchild
    So that's what caused it! I'm so glad to know that a couple of years ago, I was drinking those energy/herbal drinks, ended up lying in bed with s/s of stroke. Numb on one side of my body, including my face, drooling, and was having palpitations. I thought I was a goner for sure! (snip)
    What little research I did this afternoon for Mario (and my own curiosity), it seems as if ephedra is chemically similar to amphetamines. We've all seen those in the ER, haven't we? Try a nice amphetamine cocktail to rev you up! Then, because it's OTC, we think there isn't any danger. From an earlier post, I'll repeat myself. Personally, I don't see any problems taking these things, AS LONG AS YOU take the time to read the label and to research out the chemoactive properties of the ingredients, and take them knowing what you're taking, so -- at the very least -- you will know what side effects to watch for. You do the same for your patients, don't you?
    Last edit by Youda on Sep 17, '02

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