Is D51/4 NS hypotonic or isotonic? I know once the dextrose is metabolized in the bloodstream (in about 5 minutes), all that is left is 1/4 NS. My question is--what is the OFFICIAL stance on D51/4NS, in terms of tonicity. Different textbooks and scholarly sources say conflicting things. Help!!!
If isotonic is 280-310 mOsmol/L, and D5 !/4 NS is 321 mOsmol/L , how can it be isotonic??
Here is what I found:
Types of Hypotonic IV Solutions:
D5W (isotonic in bag, hypotonic in body d/t rapid metabolism of dextrose), 0.45% NS and 0.225 NS
Maintenance fluids: D5 ½ NS & D5 ¼ NS (hypertonic in bag, hypotonic effect in body providing water to cells; & D5NS (hypertonic in bag - less free water and more extracellular water than D5 ½ NS or D5 ¼ NS
Last edit by Brownms46 on Apr 5, '04
Quote from kona2
No worries here. I'm up for a mental challenge.
I shoulda known better than to post my response without a rationale (*you know nurses always have to know why we do things*).
Upon reflection, I have to agree the D5% and 1/4 is probably hypotonic in the body (and that's what matters). Thanks for the reply.
kona2 ...I cracked up LOL when I read (* you know nurses always have to know why we do things*)..
The first thing I thought of was "inquiring minds wanta know:chuckle:
Thank you for the response, as I have learned from this thread, and from those who chose to respond!
I was lol so much I forgot to say YOU"RE WELCOME!
Last edit by Brownms46 on Apr 7, '04