6 Alabama kids were on life support with flu - page 4

These were otherwise healthy children who came down with a severe strain of seasonal flu. The original link to the local news is included but takes forever to load so that I decided to use a link... Read More

  1. by   indigo girl
    Sometimes I am so dense. I must be slipping. It just occurred to me while vaccuuming, I do some of my best thinking then (too bad I don't do it more often), there are all these well known speakers at the CIDRAP conference.
    Then there is this doc from Birmingham, Alabama...

    He might be more well known after this conference because I think that he is going there to speak about these cases. Boy, am I slow.
  2. by   NotReady4PrimeTime
    Well, I finally had a chance to delve deeper into our very sick flu patient. She and all of our other confirmed flu cases have been flu A so far this winter. By all indication she has no underlying health issues and is on her way to a full recovery. Meanwhile we have had a bunch more RSVs, at last count we had 379 confirmed cases in our region, with 171 of those admitted to hospital and it's only January...
  3. by   indigo girl
    Thanks, janfrn,

    That confirms what I suspected all along. Now we need to know the subtype.
    I don't expect that info to be available unless some ID doc has that written in his notes. Most probably won't know it. However, I expect that the Birmingham cases have been subtyped, and sequenced. I hope that we will know more after the CIDRAP Conference. I will hate to be disappointed about this because it is important information about a public health concern. Our tax dollars are paying for this type of information to be researched, and available by CDC etc.

    Also thanks for following up about the lack of a prior existing condition. That also is important information.
    Last edit by indigo girl on Jan 17, '07
  4. by   indigo girl
    We have been expecting WHO to make an announcement about this, and they have. More sobering information about Tamiflu resistance is coming out based on viral samples from two of the three recent fatalities in Egypt. What this article does not say, but is a fact, is that the sequences were taken from the cases in Gharbiya where the case fatality ratio is 100%, and here is part of the reason why. It does not say that the viral samples were taken prior to treatment with Tamiflu, but there is a strong indication that this is so. Tamiflu resistance also occurred in Vietnam two years ago.

    Our pandemic flu plans involve the stockpiling of Tamiflu which as noted in the recent Alberta case, may not be available anyway. Countries are also beginning to stockpile Relenza which is inhaled. The question is, will that drug, which targets the respiratory tract, be enough to control a virus that attacks multiple organ systems?

    http://crofsblogs.typepad.com/h5n1/2...an_h5n1_r.html
    Last edit by indigo girl on Jan 18, '07
  5. by   indigo girl
    I have heard from a reliable source that the pediatric ICU cases in Birmingham are all Influenza A. No subtype available yet.
  6. by   indigo girl
    No prior existing conditions, 8 year old child dies from influenza in Minnesota:
    (hat tip flutrackers/wdcare)
    http://www.austindailyherald.com/art...news/news6.txt
  7. by   indigo girl
    Pediatric flu related deaths in Minnesota are type A:
    http://www.health.state.mn.us/news/p...flu020807.html
  8. by   indigo girl
    Seattle cases, one death, several hospitalized:
    http://seattlepi.nwsource.com/health...lanchet08.html
  9. by   indigo girl
    http://www.flutrackers.com/forum/sho...42&postcount=1
    http://www.flutrackers.com/forum/sho...43&postcount=2

    This is tragic. This 11 year old in Nebraska had no prior existing conditions. She also had unusual symptoms. I am not sure that I would have recognized that this was a case of influenza. I would have been looking for respiratory symptoms, for the most part, but flu can manifest via the GI tract, neurologically, and in this case via the musculoskeletal system.

    They are saying that this virus is an influenza A but, no information has been made available on the subtype, and no sequences released. Sequence information can predict virulence, ease of transmission, antiviral resistance, and other important data.

    It is important to track these cases though it may be uncomfortable to look at this information.

    Update on flu types says some are type B also:
    http://www.flutrackers.com/forum/sho...53&postcount=5
    Last edit by indigo girl on Feb 17, '07
  10. by   Jolie
    [QUOTE=indigo girl;2069986]http://www.flutrackers.com/forum/sho...42&postcount=1
    http://www.flutrackers.com/forum/sho...43&postcount=2

    This is tragic. This 11 year old had no prior existing conditions. She also had unusual symptoms. I am not sure that I would have recognized that this was a case of influenza. I would have been looking for respiratory symptoms, for the most part, but flu can manifest via the GI tract, neurologically, and in this case via the musculoskeletal system.

    They are saying that this virus is an influenza A but, no information has been made available on the subtype, and no sequences released. Sequence information can predict virulence, ease of transmission, antiviral resistance, and other important data.


    I live in Omaha, and have heard numerous news stories the past few days about this girl's death from the flu, but the above article is the first I've heard of other children hospitalized with similar muscular symptoms. What I haven't read is the mechanism by which these complications cause death. Does the muscle breakdown lead to acute renal failure? Do the respiratory muscles become paralyzed? Either of these possible scenarios would seem treatable (by dialysis or ventilator management), so I don't understand the rapid progression to death. Can anyone help me understand?

    Also, the flu season has hit our area late, and seems to be particularly harsh on children. Very few cases of complications are being reported in the elderly, as would normally be expected, but schools are reporting particularly high absence rates due to flu-like symptoms.
  11. by   Dalzac
    I just watched the news about samonella tainted peanut butter, Peter Pan and Great value brands and they numbers on the lid are 2111.
    These could very well be that cause because they present the same.
  12. by   Jolie
    Quote from Dalzac
    I just watched the news about samonella tainted peanut butter, Peter Pan and Great value brands and they numbers on the lid are 2111.
    These could very well be that cause because they present the same.
    The salmonella cases have been confirmed by stool cultures, and influenza cases have been confirmed by viral cultures. I doubt that anyone ill enough to be hospitalized with either condition would be mistakenly mis-diagnosed with the other. Also, although some of the salmonella patients have required hospitalization, all have recovered. There have been no deaths linked to this salmonella outbreak.
  13. by   indigo girl
    Jolie, no one is answering your question, and I can't really. I do not believe that this child died of renal failure. I would bet that it was multi organ failure with severe neurological involvement that would have made it pointless to continue with ECMO, dialysis and ventilation, all of which may have been tried. There seems to be a treatment protocol in place for these severe pediatric flu cases once they are identified as influenza. But, all of this is speculation on my part. Not that this is avian flu, but in avian flu cases most have died of multi organ failure, and I think that an overwhelming influenza infection would have the same result regardless of the type of influenza.

    An astute reporter could probably find out the exact cause of death. I wonder if an autopsy was done, and if death certificates are considered to be part of the public record.

    More cases are occurring in other states:

    Seattle Cases:
    http://seattletimes.nwsource.com/htm...21_flu16m.html

    Kansas Case:
    http://www.ksn.com/news/local/5888781.html

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