Originally Posted by Agnus
picc lines are no no longer flushed with heparin.
Reguardless of weather you dilute or not you need to push slow with MOST medications. GENERAL rule of thumb is 1 ml per minute. No faster. There are a few exceptions.
Lasix comes 10 per ml in the vial. Pushing it too fast can = ototoxicity.
Meds that are caustic or irritating (lasix is not one of these) or thick and or oily like Atavan should be diluted.
Dilution can help you to push a small amt of med slower but it is possible to control the rate of push if you are careful without diluting.
I agree with all of the above, but will add that Lasix (furosemide) pushed too fast will cause hypotension - 10mg/min.
Dilantin (phenytoin) and Valium (diazepam) are extremely caustic and incompatable with anything other than normal saline. Fortunately, most places now use fosphenytoin instead of phenytoin (although I had to push phenytoin a couple of months ago on the bone marrow unit - why, I don't know), and it's been many years since I've pushed diazepam. The rule for phenytoin is 50mg/min, fosphenytoin can be given at 100mg/min. Fosphenytoin is also compatable with most IV solutions.
Phenergan also needs to be diluted in 10ml of saline.
The rate of your IV fluids can also determine whether or not you need to dilute - high rates of flow can adequately dilute less caustic drugs (Ativan).
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