[kristin1978]

I give phenergan IV all the time, very slowly, over 10 minutes, and mixed with at least 10 ml of NS, with good flushes before and after. Our hospital policy states we CANNOT give phenergan in hand or wrist veins due to the fact it can cause necrosis. So now a lot of the docs are ordering Zofran instead.

[10MG-IV]

Originally Posted by NRSKarenRN

From the pharmacy experts @ Institute for Safe Medication Practices:

Action needed to prevent serious tissue injury with IV promethazine

OK, but don't take it away. Its Efficacy is huge!
learn how to give it correctly, like any other drug.


Nurses teach your young.
Don't eat them, it will leave a funny taste in your mouth.

[Babs0512]

We give IV Phenergan all the time. I've never diluted it, but I always give in with a wide open running IV and I push it slowly. I've never had anyone have a bad reaction to it in 16 years of nursing. I have, however, had several people become anxious, nasty, restless, shouting, etc... several times with Reglan. We give Benadryl, and the symptoms go away. I personally think Phenergan and Zofran work the best for nausea. That's been my experience anyway.

[nyemt195488]

I personally have been on IV phenergan off and on for the last 8 years. I suffer from non-diabetic gastroparesis and there are many times when I can not tolerate the PO phenergan. I have been on as much as 50 mg IV every 4-6 hours just to keep from needing a feeding tube. It does cause severe burning and has infact damaged a couple of my veins so now I have a mediport. The port is much nicer, no burning what so ever but I still have to push it very slowly as the port goes into the right atrium so if I dont go slow enough I feel the effect very quickly. Thankfully I carry a signed order from my gastro doc otherwise there are a few times I would not have been given it IV. Which would have left me unable to keep anything down as due to an absorption problem IM does not help, and suppositories just burn too much.

[ccuCCRN]

I've always given IV Phenergan. As everyone else has already written, make sure to dilute it. Otherwise, you are "good to go."