Originally Posted by anonymurse
A lot depends on the value I attach to having a reliable site instantly available (depends on pt instability), plus how hard it is to get a line on that pt, vs. pt convenience (mobility). Also the more times you screw a luer lock on or off the INT, the looser it may get. Considering the magnitude of risk for infection involved in putting a hole in a pt's skin that goes directly into the bloodstream, I personally don't worry too much about the finer points of "infection rate of frequently accessed ports vs. closed system of IV tubing with piggybacks" although it would be interesting to know.
You can always change the lock if it get loose......