Originally Posted by CBER
The references I looked at states that phenergan can be given IV push diluted or not.Look at the infusion nurses society about the ph of drugs. Phenergan does not fall into a drug that is safe to push in a perioheral line. I just read an article where phenergan was blamed for the loss of an arm. I hope this helps. Also the reference I looked at stated it should be given through a running IV.Diluting the phenergan with any amount of ns does not change the ph of the drug.
It will not change the pH of the medication itself, but diluting any drug in a large quantity of neutral solution (like NS) will bring the pH closer to neutral.
You can try this experiment at home. Take vinegar and add water to it. It will not be as acidic as when it is straight from the bottle. Same principle applied here.
Chip