For upper extremities that develop DVT's around the PICC line we remove the PICC line if it's an occlusive thrombus or if the MD requests the line to be removed. If it's a nonocclusive thrombus the line doesn't necessarily have to be removed. Warm soaks and elevation work well. As well as some form of anticoagulation therapy should be started if the patients' condition allows. Any other questions feel free to email me.