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I don't dilute it. The one and only time I did was for a huge dose (200mg for a renal patient) that I put in a 50cc NS piggyback so I wouldn't have to stand there forever to push it.
The only reason to diulte lasix would be to get it into enough volume to make it easier to "control" when pushing it over a long time (it is difficult to push .5 cc over 5 min).
Lasix is usually 10 mg/cc, and is fairly easy to push it .5 cc every 30 sec or so.
When I've given large doses (200 mg), I worked in a unit that had syringe pumps and I could put it in the syringe pump and have it go over 20 min. Otherwise, I agree with above and would put it in 50 cc NS and infuse it over 30 min. for convenience.
Otherwise, don't dilute it, just push it at 10 mg/min.
I learned in school and always keep this in the back of my mind. 1mL per 1 minute. This does not apply to all meds, but is a good reference. I don't dilute Lasix, but you can if you are more comfortable administering that way. ALWAYS consult a drug book if you are in doubt. Don't take anyone's word for it- even if they have been doing this for years....
According to my drug book, and our practice, infusions of Lasix are to be no faster than 4 (four) mg/min. If giving IVP, the book says no faster than 20 mg/min. In fact, in peds, we never give faster than 4 mg/min.
I agree with crb...always look up the drug if you are unsure or have questions about it. It's your patient and your responsibility to act in their best interests and to ensure their safety.