I'm applying to two ABSN/MSN combo programs and two ABSN programs, for a summer or fall 2008 start. I'd prefer to enter one of the combo programs, but included reputable and highly recommended ABSN programs as extra options. It was important to me to cast a wide net as last year I applied to only one DEMSN program and was not accepted.
If do get accepted to the combo program (JHU & Columbia) and choose to attend either one, the advantage is that I would have the opportunity to go directly into the MSN portion (or take a break to gain bedside experience), without having to apply to a grad program again.
If I do not get accepted to those, but to one of the ABSN programs, I'll have a chance to get a start on my path in a great program.
I'd say investigate specific programs that fit your criteria and apply to a combination of different programs. When notifications are made for all of them, then the decision making will really begin on your part and you can weigh the pros/cons.
Good luck!