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We hang it IVPB, with a special inline filter below the pump. If it is necessary to use the filter IVPB I would be concerned about using the drug IVP. The filter is packaged by and for the express use of Pepcid. It is diluted in 50 ml NS after first reconstituting with 5 ml sterile water for injection (per instructions on bottle). It may depend on the manufacturer and it's manufacturing process whether it needs a filter or not. I cannot remember if we have generic or brand name.
Pharmacy sends up pepcid separate and not from the pyxis, a 10 cc saline is included in the bag. But if you don't want to dilute it, just give it over 2 minutes. There shouldn't be hemodynamic changes if it's two minutes even if it is undiluted.