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IV Dex for PO Dex?



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  #1  
Old Jul 07, 2007, 09:15 PM
Registered User
Join Date: May 2007
IV Dex for PO Dex?

I have started working in a new hospital that uses IV dexamethasone when it is ordered po for pediatric patients that cannot swallow pills. You draw the prescribed amount out of the vial that is ordered and mix it with cherry syrup. This is what is traditional practice instead of crushing the pills and dissolving them in cherry syrup. The argument is that when the pills are crushed, you lose some of the medication, so using the IV dex is a more accurate means of giving the desired dose.

So, has anyone else ever heard of this practice? Does anyone have any resources regarding the efficacy and safety of this practice? Plus what about the taste? Does this produce more or less of a "vomit factor" than when giving prednisolone or crushed dexamethasone tablets?

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  #2  
Old Jul 07, 2007, 09:38 PM
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Join Date: Mar 2007
Re: IV Dex for PO Dex?

Originally Posted by stayseerrn View Post
I have started working in a new hospital that uses IV dexamethasone when it is ordered po for pediatric patients that cannot swallow pills. You draw the prescribed amount out of the vial that is ordered and mix it with cherry syrup. This is what is traditional practice instead of crushing the pills and dissolving them in cherry syrup. The argument is that when the pills are crushed, you lose some of the medication, so using the IV dex is a more accurate means of giving the desired dose.

So, has anyone else ever heard of this practice? Does anyone have any resources regarding the efficacy and safety of this practice? Plus what about the taste? Does this produce more or less of a "vomit factor" than when giving prednisolone or crushed dexamethasone tablets?


I gave this for the first time last night ...

we give it in ibuprofen to kill the taste. My pt (8 yrs old) swallowed it like a champ, and chased it down with some Sprite. He didn't vomit at all.

Sorry .. I don't have any info about the efficacy/safety. Did you check with your pharmacist??

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  #3  
Old Jul 07, 2007, 11:29 PM
NREMT-P/RN (Female)
Senior Member
Join Date: Apr 2006
Re: IV Dex for PO Dex?

I have given it like that in several facilities. Double check with YOUR pharmacy - but I have never had ANY problems. (As long as you "mask" the taste!)

Great idea, IMHO and no needles!

Practice SAFE!


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  #4  
Old Jul 08, 2007, 01:20 PM
Registered User
Join Date: Dec 2002
Re: IV Dex for PO Dex?

We do this all the time. It beats giving them a shot any day!

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  #5  
Old Jul 09, 2007, 10:50 AM
Registered User
Join Date: Mar 2006
Re: IV Dex for PO Dex?

We do this as well, but generally mix it with Tylenol. Can't imagine it tastes good at all! Agreed - beats giving a kiddo a shot!!!

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  #6  
Old Jul 10, 2007, 03:11 PM
Senior Member
Join Date: May 2001
Re: IV Dex for PO Dex?

do it all the time

works as well

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  #7  
Old Jul 10, 2007, 10:40 PM
Registered User
Join Date: Jul 2007
Re: IV Dex for PO Dex?

Very interesting. I will have to submit this to our pharmacy.

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  #8  
Old Jul 11, 2007, 11:59 AM
Registered User
Join Date: Aug 2004
Re: IV Dex for PO Dex?

Steroids generally have a slow onset of action so PO is just as efficacious.

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  #9  
Old Jul 12, 2007, 07:55 PM
canoehead's Avatar
canoehead (Female)
Senior Member
Join Date: Oct 2000
Re: IV Dex for PO Dex?

Yep, we do that. IV is more concentrated and lowers the volume the kids have to take. 1ml vrs 30ml

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  #10  
Old Jul 13, 2007, 12:02 AM
Registered User
Join Date: Jun 2005
Re: IV Dex for PO Dex?

Originally Posted by stayseerrn View Post
I have started working in a new hospital that uses IV dexamethasone when it is ordered po for pediatric patients that cannot swallow pills. You draw the prescribed amount out of the vial that is ordered and mix it with cherry syrup. This is what is traditional practice instead of crushing the pills and dissolving them in cherry syrup. The argument is that when the pills are crushed, you lose some of the medication, so using the IV dex is a more accurate means of giving the desired dose.

So, has anyone else ever heard of this practice? Does anyone have any resources regarding the efficacy and safety of this practice? Plus what about the taste? Does this produce more or less of a "vomit factor" than when giving prednisolone or crushed dexamethasone tablets?
We use IV Dex all the time, I mix it with apple juice and have a popsicle handy

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IV Dex for PO Dex?

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