Originally Posted by WntrMute2
I'm assuming that the maxumum amounts of epinepnine and lidocane need to be factored in. How would you calculate the fluid limit, the drugs have pretty specific guidelines to follow or is there something different about that too?
Thanks in advance.
It is very difficult to calculate maximum doses of lidocaine and epinephrine. Some dermatology literature states that over 50 mg/kg of lidocaine can safely be used with tumescent anesthesia. Those doses are too high for my comfort. The reason why it is difficult to calculate doses is because it is very slowly absorbed from the fat and some of it is suctioned out. Studies pubished in the literature show that the maximum plasma levels of lidocaine peak at 6-8 hours post infiltration.
There have been a lot of deaths from tumescent liposuction, because of overdose, excessive bleeding and inadequate fluid replacement.
A Medline search on this topic is very useful.
YogaCRNA