I live in Jacksonville. There are a couple hospitals here in the city. I work at Baptist Medical Center which is really 4 different hospitals that are a system (Downtown, South, Beaches, and Nassau.) Its also a Magnet hospital.There is also Shands which is a trauma hospital, St Lukes and St. Vincents (2 hospitals but they have merged.), Memorial and Orange Park. There is also a Naval hospital on base. It kind of depends on what you are looking for. Pay wise Baptist has the lowest pay but I personally can't see myself working in the other hospitals here in the city, but don't bother applying if you don't have your BSN. I would stay away from Heartland (nursing/rehab) just because everyone that I know that has worked there has had bad experiences. I have a couple of friends that work at Brooks rehab and they love it. Jobs are tough to come by if you don't have nursing experience.
Living wise, I live in Arlington which is considered the ghetto by some but I live in a really nice area. *shrugs* Riverside and San Marco are nice if you like more of that hip, young yet at the same old timey feel. Southside has alot of apartments and nice areas as well. Its a bit pricey close to the beach but its a really nice area. I would stay away from downtown. Northside is more of the woodsy country area. Near the St. Johns Town Center is where most of the new things are popping up. Mandarin and San Jose areas are really nice. Orange Park is ok IMO.
Public school system sucks. I mean its really really bad.
Everyone says Jacksonville is violent but I don't really see much of that where I live. Closer to downtown yes, but surrounding that not so much.
Jacksonville is big.
Plan to have a good car, because you have to drive everywhere.
Hope that helps.